Cost-effectiveness of populationwide educational approaches to reduce serum cholesterol levels
Background The aim of the present study was to estimate the cost-effectiveness of populationwide approaches to reduce serum cholesterol levels in the US adult population. Methods and Results This cost-effectiveness analysis was made from data from the literature and the Coronary Heart Disease Policy...
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ftunigroningenpu:oai:pure.rug.nl:publications/0b422101-b61a-4e35-8bd5-4539552c3001 2024-06-02T08:09:46+00:00 Cost-effectiveness of populationwide educational approaches to reduce serum cholesterol levels Tosteson, ANA Weinstein, MC Hunink, MGM Mittleman, MA Williams, LW Goldman, PA Goldman, L 1997-01-07 https://hdl.handle.net/11370/0b422101-b61a-4e35-8bd5-4539552c3001 https://research.rug.nl/en/publications/0b422101-b61a-4e35-8bd5-4539552c3001 eng eng https://research.rug.nl/en/publications/0b422101-b61a-4e35-8bd5-4539552c3001 info:eu-repo/semantics/restrictedAccess Tosteson , ANA , Weinstein , MC , Hunink , MGM , Mittleman , MA , Williams , LW , Goldman , PA & Goldman , L 1997 , ' Cost-effectiveness of populationwide educational approaches to reduce serum cholesterol levels ' , Circulation , vol. 95 , no. 1 , pp. 24-30 . cholesterol coronary disease cost-benefit analysis prevention CORONARY HEART-DISEASE RISK-FACTORS BLOOD CHOLESTEROL CARDIOVASCULAR-DISEASE INTERVENTION TRIAL LIFE EXPECTANCY UNITED-STATES POLICY MODEL MORTALITY HEALTH article 1997 ftunigroningenpu 2024-05-07T19:14:41Z Background The aim of the present study was to estimate the cost-effectiveness of populationwide approaches to reduce serum cholesterol levels in the US adult population. Methods and Results This cost-effectiveness analysis was made from data from the literature and the Coronary Heart Disease Policy Model and was based on the US population age 35 to 84 years. Study interventions were populationwide programs to reduce serum cholesterol levels with costs and cholesterol-lowering effects similar to those reported from the Stanford Three-Community Study, the Stanford Five-City Project, and in North Karelia, Finland. The main outcome measures were cost-effectiveness ratios, defined as the change in projected cost divided by the change in projected life-years when the population receives the intervention compared with the population without the intervention. A populationwide program with the costs ($4.95 per person per year) and cholesterol-lowering effects (an average 2% reduction in serum cholesterol levels) of the Stanford Five-City Project would prolong life at an estimated cost of only $3200 per year of life saved. Under a wide variety of assumptions, a populationwide program would achieve health benefits at a cost equivalent to that of many currently accepted medical interventions. Such programs would also lengthen life and save resources under many scenarios, especially if the program affected persons with preexisting heart disease or altered other coronary risk factors. Conclusions Populationwide programs should be part of any national health strategy to reduce coronary heart disease. Article in Journal/Newspaper karelia* University of Groningen research database |
institution |
Open Polar |
collection |
University of Groningen research database |
op_collection_id |
ftunigroningenpu |
language |
English |
topic |
cholesterol coronary disease cost-benefit analysis prevention CORONARY HEART-DISEASE RISK-FACTORS BLOOD CHOLESTEROL CARDIOVASCULAR-DISEASE INTERVENTION TRIAL LIFE EXPECTANCY UNITED-STATES POLICY MODEL MORTALITY HEALTH |
spellingShingle |
cholesterol coronary disease cost-benefit analysis prevention CORONARY HEART-DISEASE RISK-FACTORS BLOOD CHOLESTEROL CARDIOVASCULAR-DISEASE INTERVENTION TRIAL LIFE EXPECTANCY UNITED-STATES POLICY MODEL MORTALITY HEALTH Tosteson, ANA Weinstein, MC Hunink, MGM Mittleman, MA Williams, LW Goldman, PA Goldman, L Cost-effectiveness of populationwide educational approaches to reduce serum cholesterol levels |
topic_facet |
cholesterol coronary disease cost-benefit analysis prevention CORONARY HEART-DISEASE RISK-FACTORS BLOOD CHOLESTEROL CARDIOVASCULAR-DISEASE INTERVENTION TRIAL LIFE EXPECTANCY UNITED-STATES POLICY MODEL MORTALITY HEALTH |
description |
Background The aim of the present study was to estimate the cost-effectiveness of populationwide approaches to reduce serum cholesterol levels in the US adult population. Methods and Results This cost-effectiveness analysis was made from data from the literature and the Coronary Heart Disease Policy Model and was based on the US population age 35 to 84 years. Study interventions were populationwide programs to reduce serum cholesterol levels with costs and cholesterol-lowering effects similar to those reported from the Stanford Three-Community Study, the Stanford Five-City Project, and in North Karelia, Finland. The main outcome measures were cost-effectiveness ratios, defined as the change in projected cost divided by the change in projected life-years when the population receives the intervention compared with the population without the intervention. A populationwide program with the costs ($4.95 per person per year) and cholesterol-lowering effects (an average 2% reduction in serum cholesterol levels) of the Stanford Five-City Project would prolong life at an estimated cost of only $3200 per year of life saved. Under a wide variety of assumptions, a populationwide program would achieve health benefits at a cost equivalent to that of many currently accepted medical interventions. Such programs would also lengthen life and save resources under many scenarios, especially if the program affected persons with preexisting heart disease or altered other coronary risk factors. Conclusions Populationwide programs should be part of any national health strategy to reduce coronary heart disease. |
format |
Article in Journal/Newspaper |
author |
Tosteson, ANA Weinstein, MC Hunink, MGM Mittleman, MA Williams, LW Goldman, PA Goldman, L |
author_facet |
Tosteson, ANA Weinstein, MC Hunink, MGM Mittleman, MA Williams, LW Goldman, PA Goldman, L |
author_sort |
Tosteson, ANA |
title |
Cost-effectiveness of populationwide educational approaches to reduce serum cholesterol levels |
title_short |
Cost-effectiveness of populationwide educational approaches to reduce serum cholesterol levels |
title_full |
Cost-effectiveness of populationwide educational approaches to reduce serum cholesterol levels |
title_fullStr |
Cost-effectiveness of populationwide educational approaches to reduce serum cholesterol levels |
title_full_unstemmed |
Cost-effectiveness of populationwide educational approaches to reduce serum cholesterol levels |
title_sort |
cost-effectiveness of populationwide educational approaches to reduce serum cholesterol levels |
publishDate |
1997 |
url |
https://hdl.handle.net/11370/0b422101-b61a-4e35-8bd5-4539552c3001 https://research.rug.nl/en/publications/0b422101-b61a-4e35-8bd5-4539552c3001 |
genre |
karelia* |
genre_facet |
karelia* |
op_source |
Tosteson , ANA , Weinstein , MC , Hunink , MGM , Mittleman , MA , Williams , LW , Goldman , PA & Goldman , L 1997 , ' Cost-effectiveness of populationwide educational approaches to reduce serum cholesterol levels ' , Circulation , vol. 95 , no. 1 , pp. 24-30 . |
op_relation |
https://research.rug.nl/en/publications/0b422101-b61a-4e35-8bd5-4539552c3001 |
op_rights |
info:eu-repo/semantics/restrictedAccess |
_version_ |
1800755542894837760 |