Cost-effectiveness of populationwide educational approaches to reduce serum cholesterol levels

Background The aim of the present study was to estimate the cost-effectiveness of populationwide approaches to reduce serum cholesterol levels in the US adult population. Methods and Results This cost-effectiveness analysis was made from data from the literature and the Coronary Heart Disease Policy...

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Bibliographic Details
Main Authors: Tosteson, ANA, Weinstein, MC, Hunink, MGM, Mittleman, MA, Williams, LW, Goldman, PA, Goldman, L
Format: Article in Journal/Newspaper
Language:English
Published: 1997
Subjects:
cholesterol
coronary disease
cost-benefit analysis
prevention
CORONARY HEART-DISEASE
RISK-FACTORS
BLOOD CHOLESTEROL
CARDIOVASCULAR-DISEASE
INTERVENTION TRIAL
LIFE EXPECTANCY
UNITED-STATES
POLICY MODEL
MORTALITY
HEALTH
karelia*
Online Access:https://hdl.handle.net/11370/0b422101-b61a-4e35-8bd5-4539552c3001
https://research.rug.nl/en/publications/0b422101-b61a-4e35-8bd5-4539552c3001
Description
Summary:Background The aim of the present study was to estimate the cost-effectiveness of populationwide approaches to reduce serum cholesterol levels in the US adult population. Methods and Results This cost-effectiveness analysis was made from data from the literature and the Coronary Heart Disease Policy Model and was based on the US population age 35 to 84 years. Study interventions were populationwide programs to reduce serum cholesterol levels with costs and cholesterol-lowering effects similar to those reported from the Stanford Three-Community Study, the Stanford Five-City Project, and in North Karelia, Finland. The main outcome measures were cost-effectiveness ratios, defined as the change in projected cost divided by the change in projected life-years when the population receives the intervention compared with the population without the intervention. A populationwide program with the costs ($4.95 per person per year) and cholesterol-lowering effects (an average 2% reduction in serum cholesterol levels) of the Stanford Five-City Project would prolong life at an estimated cost of only $3200 per year of life saved. Under a wide variety of assumptions, a populationwide program would achieve health benefits at a cost equivalent to that of many currently accepted medical interventions. Such programs would also lengthen life and save resources under many scenarios, especially if the program affected persons with preexisting heart disease or altered other coronary risk factors. Conclusions Populationwide programs should be part of any national health strategy to reduce coronary heart disease.

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