| Summary: | Objective: The aim of this study was to conduct a scoping review through a systematic analysis of reviews investigating the effect of neural mobilization (NM), either alone or combined with other interventions, in individuals with carpal tunnel syndrome (CTS), across different clinical and functional outcomes. Method: A systematic search was conducted in the following databases: PubMed, SciELO, and PEDro. The search period spanned from October 20 to October 30, 2023. The population consisted of individuals diagnosed with CTS; the studied intervention was the NM technique applied alone or in combination; the comparison included control, placebo, simulation, or sham intervention; outcomes were not pre-determined. The methodological quality of the studies was assessed using the AMSTAR-2 tool. Results: A total of 26 articles were found. Among these, one was a duplicate, three were excluded at the title level, and 15 were excluded during abstract review, resulting in seven articles. After a full-text review, two articles were excluded, leaving five studies included in this review. Participant ages ranged from 18 to 85 years, including both men and women. The most evaluated outcomes were pain and function, measured using the Numerical Pain Rating Scale (NPRS), Visual Analog Scale for Pain (VAS), Mechanical Visual Analog Scale (MVAS), West Haven-Yale Multidimensional Pain Inventory (WHYMPI), and Boston Carpal Tunnel Syndrome Questionnaire (BCTS-Q). Nerve conduction velocity was also assessed through electroneuromyography (ENMG), Distal Sensory Latency (DSL), and Distal Motor Latency (DML). Reduction in pain and improvement in function were observed with median nerve mobilization, along with enhanced nerve conduction. Conclusion: This study suggests that neural mobilization techniques may have positive effects on reducing pain, improving function, and enhancing nerve conduction in patients with CTS. However, it is important to note that the definitive conclusion regarding the efficacy of these techniques is limited due ...
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