| Summary: | At the present study we determined the phitoconstituyent Psoralea glandulosa leaves and its hipogliceming effect in Rattus rattus var albinos. Determination of the phitoconstituyent was used the March Phitochimestry Olga Lock adapated by Casanova.Being the following fitoconstitutives: phenoles, flavonoids, tanins. To check the hipoglicemic effect of the leaves infuse of Psoralea glandulosa 24 animals was distributed in four groups. Group I they were administered solutio of glucose for oral way to the doses of 2.5 g/kg.c.w. and derterminate the glicemi respectively by diferent time: 30, 60, 90, 120 minutes In the second group they were administered infuse by 160 mg/dL. and glucose solution and repeat the same method as first group. The group III determinate intestinal absortion with glucose solution and infuse with glucose then determinated the glucose value. Enzymatic method was used for the determinations of glucose,being that the infuse to the dose 160 mg/dL of c.w. it exercises hipoglicemic effect,being statistically this value significant ( P< 0.05). We conclude that the infuse of leaves of Psoralea glandulosa has hipoglicemic effect. En el presente trabajo se ha determinado los fitoconstituyentes de las hojas de Psoralea Glandulosa y su efecto hipoglicemiante en Rattus rattus var. albinus con hiperglicemia experimental. Para la determinación de los fitoconstituyentes se utilizó la marcha fitoquímica de Olga Lock adaptada por Hugo casanova H. Encontrándose los siguientes fitoconstituyentes: fenoles, flavonoides y taninos. Para comprobar el efecto hipoglicemiante del infuso de hojas de Psoralea glandulosa se utilizó 24 animales de experimentación los que se dividieron en cuatro grupos .Al grupo I se les administró una sobrecarga de glucosa a la dosis de 2.5 g por Kg.p.c. determinándoles su glicemia basal y a intervalos de 30, 60,90 y 120 minutos; al grupo II se le administró junto a la sobrecarga de glucosa el infuso a la dosis de 160 mg/Kg, siguiendo los mismos pasos del primer grupo. Al grupo III se ...
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