Update on CDV strains of Arctic-like lineage detected from dogs in Italy
Canine distemper virus (CDV) is the etiologic agent of distemper in dogs. It exhibits an elevated potential of crossing species barriers, infecting a wide range of wild and domestic carnivores. Of its encoding genes, hemagglutinin (H) shows high heterogeneity, and it was used to determine the relati...
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ftunibolognairis:oai:cris.unibo.it:11585/662222 2024-02-11T10:00:04+01:00 Update on CDV strains of Arctic-like lineage detected from dogs in Italy Mira F Purpari G Di Bella S Vicari D Schirò G Di Marco P Macaluso G Battilani M Guercio A. Mira F, Purpari G, Di Bella S, Vicari D, Schirò G, Di Marco P, Macaluso G, Battilani M, Guercio A. 2018 STAMPA http://hdl.handle.net/11585/662222 https://doi.org/10.12834/VetIt.1455.7862.2 http://www.izs.it/vet_italiana/2018/54_3/VetIt_1455_7862_2.pdf eng eng info:eu-repo/semantics/altIdentifier/pmid/30575000 info:eu-repo/semantics/altIdentifier/wos/WOS:000454820000007 volume:54 issue:3 firstpage:225 lastpage:236 numberofpages:12 journal:VETERINARIA ITALIANA http://hdl.handle.net/11585/662222 doi:10.12834/VetIt.1455.7862.2 info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85058568225 http://www.izs.it/vet_italiana/2018/54_3/VetIt_1455_7862_2.pdf info:eu-repo/semantics/openAccess Biological evolution Canine distemper viru Dog Europe Genomic Hemagglutinin info:eu-repo/semantics/article 2018 ftunibolognairis https://doi.org/10.12834/VetIt.1455.7862.2 2024-01-24T17:53:26Z Canine distemper virus (CDV) is the etiologic agent of distemper in dogs. It exhibits an elevated potential of crossing species barriers, infecting a wide range of wild and domestic carnivores. Of its encoding genes, hemagglutinin (H) shows high heterogeneity, and it was used to determine the relationship between CDV strains due to its variability and key role in determining cell tropism, host shift, and in eliciting a protective immune response. This study analysed the full-length H gene sequence of Arctic-like CDV strains collected from dogs in Italy during a period in which an increased activity of CDV diffusion was observed. The common amino acid changes and features of Arctic-like CDV strains collected from 2011 to 2016 in Europe were described, providing an updated analysis of the genomic features. A comparison with CDV vaccine strains was carried out to evaluate the increased genomic difference with CDV Arctic-like field strains. This study provides a complete and updated analysis of the current spreading strains of Arctic-like lineage and the main amino acid variations in the hemagglutinin gene sequence circulating in Italy. Moreover, it provides novel information regarding the evolution of the most recent CDV Arctic-like lineage strains collected in Europe. Article in Journal/Newspaper Arctic IRIS Università degli Studi di Bologna (CRIS - Current Research Information System) Arctic |
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IRIS Università degli Studi di Bologna (CRIS - Current Research Information System) |
op_collection_id |
ftunibolognairis |
language |
English |
topic |
Biological evolution Canine distemper viru Dog Europe Genomic Hemagglutinin |
spellingShingle |
Biological evolution Canine distemper viru Dog Europe Genomic Hemagglutinin Mira F Purpari G Di Bella S Vicari D Schirò G Di Marco P Macaluso G Battilani M Guercio A. Update on CDV strains of Arctic-like lineage detected from dogs in Italy |
topic_facet |
Biological evolution Canine distemper viru Dog Europe Genomic Hemagglutinin |
description |
Canine distemper virus (CDV) is the etiologic agent of distemper in dogs. It exhibits an elevated potential of crossing species barriers, infecting a wide range of wild and domestic carnivores. Of its encoding genes, hemagglutinin (H) shows high heterogeneity, and it was used to determine the relationship between CDV strains due to its variability and key role in determining cell tropism, host shift, and in eliciting a protective immune response. This study analysed the full-length H gene sequence of Arctic-like CDV strains collected from dogs in Italy during a period in which an increased activity of CDV diffusion was observed. The common amino acid changes and features of Arctic-like CDV strains collected from 2011 to 2016 in Europe were described, providing an updated analysis of the genomic features. A comparison with CDV vaccine strains was carried out to evaluate the increased genomic difference with CDV Arctic-like field strains. This study provides a complete and updated analysis of the current spreading strains of Arctic-like lineage and the main amino acid variations in the hemagglutinin gene sequence circulating in Italy. Moreover, it provides novel information regarding the evolution of the most recent CDV Arctic-like lineage strains collected in Europe. |
author2 |
Mira F, Purpari G, Di Bella S, Vicari D, Schirò G, Di Marco P, Macaluso G, Battilani M, Guercio A. |
format |
Article in Journal/Newspaper |
author |
Mira F Purpari G Di Bella S Vicari D Schirò G Di Marco P Macaluso G Battilani M Guercio A. |
author_facet |
Mira F Purpari G Di Bella S Vicari D Schirò G Di Marco P Macaluso G Battilani M Guercio A. |
author_sort |
Mira F |
title |
Update on CDV strains of Arctic-like lineage detected from dogs in Italy |
title_short |
Update on CDV strains of Arctic-like lineage detected from dogs in Italy |
title_full |
Update on CDV strains of Arctic-like lineage detected from dogs in Italy |
title_fullStr |
Update on CDV strains of Arctic-like lineage detected from dogs in Italy |
title_full_unstemmed |
Update on CDV strains of Arctic-like lineage detected from dogs in Italy |
title_sort |
update on cdv strains of arctic-like lineage detected from dogs in italy |
publishDate |
2018 |
url |
http://hdl.handle.net/11585/662222 https://doi.org/10.12834/VetIt.1455.7862.2 http://www.izs.it/vet_italiana/2018/54_3/VetIt_1455_7862_2.pdf |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_relation |
info:eu-repo/semantics/altIdentifier/pmid/30575000 info:eu-repo/semantics/altIdentifier/wos/WOS:000454820000007 volume:54 issue:3 firstpage:225 lastpage:236 numberofpages:12 journal:VETERINARIA ITALIANA http://hdl.handle.net/11585/662222 doi:10.12834/VetIt.1455.7862.2 info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85058568225 http://www.izs.it/vet_italiana/2018/54_3/VetIt_1455_7862_2.pdf |
op_rights |
info:eu-repo/semantics/openAccess |
op_doi |
https://doi.org/10.12834/VetIt.1455.7862.2 |
_version_ |
1790595782342082560 |