Vitamin D status and bone and connective tissue turnover in brown bears (Ursus arctos) during hibernation and the active state

Extended physical inactivity causes disuse osteoporosis in humans. In contrast, brown bears (Ursus arctos) are highly immobilised for half of the year during hibernation without signs of bone loss and therefore may serve as a model for prevention of osteoporosis.

Bibliographic Details
Published in:PLoS ONE
Main Authors: Vestergaard, Peter, Støen, Ole-Gunnar, Swenson, Jon E, Mosekilde, Leif, Heickendorff, Lene, Fröbert, O
Format: Article in Journal/Newspaper
Language:English
Published: 2011
Subjects:
Online Access:https://pure.au.dk/portal/da/publications/vitamin-d-status-and-bone-and-connective-tissue-turnover-in-brown-bears-ursus-arctos-during-hibernation-and-the-active-state(283c711f-ddca-4718-9fa6-c753cf75230d).html
https://doi.org/10.1371/journal.pone.0021483
Description
Summary:Extended physical inactivity causes disuse osteoporosis in humans. In contrast, brown bears (Ursus arctos) are highly immobilised for half of the year during hibernation without signs of bone loss and therefore may serve as a model for prevention of osteoporosis.