Cadmium Toxicity to Ringed Seals (Phoca hispida):An Epidemiological Study of Possible Cadmium Induced Nephropathy and Osteodystrophy in Ringed Seals (Phoca hispida) from Qaanaaq in Northwest Greenland

Cadmium concentrations in kidneys from ringed seals (Phoca hispida) from North West Greenland (Qaanaaq) are high. Concentrations range at level known to induce renal toxic effects (mainly tubulopathy) and demineralisation (osteopenia) of the skeletal system (Fanconi's Syndrome) in humans as wel...

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Bibliographic Details
Main Authors: Sonne, Christian, Dietz, R., Riget, F. F., Leifsson, P. S., Hyldstrup, L.
Format: Book
Language:English
Published: National Environmental Research Institute 2000
Subjects:
cadmium
North West Greenland
ringed seal (Phoca hispida)
renal toxicology
skeletal demineralisation (osteopenia)
food composition
physiologic adaptation
Greenland
Qaanaaq
Phoca hispida
ringed seal
Online Access:https://pure.au.dk/portal/da/publications/cadmium-toxicity-to-ringed-seals-phoca-hispida(22ebb1e0-7e9d-11dd-a5a8-000ea68e967b).html
http://www2.dmu.dk/1_viden/2_Publikationer/3_fagrapporter/rapporter/FR307.pdf
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Summary:Cadmium concentrations in kidneys from ringed seals (Phoca hispida) from North West Greenland (Qaanaaq) are high. Concentrations range at level known to induce renal toxic effects (mainly tubulopathy) and demineralisation (osteopenia) of the skeletal system (Fanconi's Syndrome) in humans as well as laboratory mammals. We have studied possible cadmium induced histopathological changes in the kidneys as well as a demineralisation of the skeletal system (DXA-scanning of lumbal vertebraes). No obvious cadmium induced toxic changes were found. Food composition and physiological adaptations may explain the absence of toxic effects of cadmium in ringed seal

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