Enkephalin-immunoreactive cells in the mesencephalic tegmentum project to the optic tectum of the teleosts Salmo gairdneri and Salmo salar

Immunocytochemistry using antibodies against Met-enkephalin and Leu-enkephalin has demonstrated a group of large enkephalin-immunoreactive neurons in the nucleus of the rostral mesencephalic tegmentum (mRMT) of two teleost fish, Salmo gairdneri and Salmo salar. Injections of cobalt-lysine in the med...

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Bibliographic Details
Published in:Cell and Tissue Research
Main Authors: Vecino, Elena, Ekström, Peter, Sharma, Sansar C.
Format: Article in Journal/Newspaper
Language:English
Published: Springer 1991
Subjects:
Cobalt-lysine
Enkephalins
Immunocytochemistry
Retrograde labeling
Salmo gairdneri
Salmo salar (Teleostei)
Tectum opticum
Tegmentum mesencephali
Salmo salar
Online Access:https://lup.lub.lu.se/record/ca349a22-5990-445e-bc05-abc9f6318fe3
https://doi.org/10.1007/BF00305731
Description
Summary:Immunocytochemistry using antibodies against Met-enkephalin and Leu-enkephalin has demonstrated a group of large enkephalin-immunoreactive neurons in the nucleus of the rostral mesencephalic tegmentum (mRMT) of two teleost fish, Salmo gairdneri and Salmo salar. Injections of cobalt-lysine in the medial optic tectum retrogradely labeled the above group of tegmental neurons. Tegmental neurons were labeled only ipsilaterally to the injection site. This indicates that enkephalinergic neurons in the nRMT project to the optic tectum, and that at least some of the enkephalinergic axons observed in the optic tectum belong to a tegmento-tectal pathway. Comparable enkephalinergic pathways have been described in reptiles and birds, where pretectal-mesencephalic nuclei contribute to the enkephalin-containing fibers that project to the optic tectum.

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