Local Contrasts in Concentration of Ambient Particulate Air Pollution (PM2.5) and Incidence of Alzheimer's Disease and Dementia : Results from the Betula Cohort in Northern Sweden
Exposure to fine particulate air pollution (PM2.5) is emerging as a risk factor for Alzheimer's disease (AD), but existing studies are still limited and heterogeneous. We have previously studied the association between dementia (AD and vascular dementia) and PM2.5 stemming from vehicle exhaust...
Published in: | Journal of Alzheimer's Disease |
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Format: | Article in Journal/Newspaper |
Language: | English |
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IOS Press
2021
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Online Access: | https://lup.lub.lu.se/record/9f4758c7-29f9-4de1-b5ee-01a67a544c22 https://doi.org/10.3233/JAD-201538 |
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ftulundlup:oai:lup.lub.lu.se:9f4758c7-29f9-4de1-b5ee-01a67a544c22 2024-05-19T07:46:05+00:00 Local Contrasts in Concentration of Ambient Particulate Air Pollution (PM2.5) and Incidence of Alzheimer's Disease and Dementia : Results from the Betula Cohort in Northern Sweden Aström, Daniel Oudin Adolfsson, Rolf Segersson, David Forsberg, Bertil Oudin, Anna 2021 https://lup.lub.lu.se/record/9f4758c7-29f9-4de1-b5ee-01a67a544c22 https://doi.org/10.3233/JAD-201538 eng eng IOS Press https://lup.lub.lu.se/record/9f4758c7-29f9-4de1-b5ee-01a67a544c22 http://dx.doi.org/10.3233/JAD-201538 scopus:85105728122 pmid:33749652 Journal of Alzheimer's Disease; 81(1), pp 83-85 (2021) ISSN: 1387-2877 Environmental Health and Occupational Health Air pollution Alzheimer's disease dementia particulate air pollution PM contributiontojournal/systematicreview info:eu-repo/semantics/article text 2021 ftulundlup https://doi.org/10.3233/JAD-201538 2024-04-23T23:58:21Z Exposure to fine particulate air pollution (PM2.5) is emerging as a risk factor for Alzheimer's disease (AD), but existing studies are still limited and heterogeneous. We have previously studied the association between dementia (AD and vascular dementia) and PM2.5 stemming from vehicle exhaust and wood-smoke in the Betula cohort in Northern Sweden. The aim of this commentary is to estimate the association between total PM2.5 and dementia in the Betula cohort, which is more relevant to include in future meta-estimates than the source-specific estimates. The hazard ratio for incident dementia associated with a 1µg/m3 increase in local PM2.5 was 1.38 (95% confidence interval: 0.99 -1.92). The interpretation of our results is that they indicate an association between local contrasts in concentration of PM2.5 at the residential address and incidence of dementia in a low-level setting. Article in Journal/Newspaper Northern Sweden Lund University Publications (LUP) Journal of Alzheimer's Disease 81 1 83 85 |
institution |
Open Polar |
collection |
Lund University Publications (LUP) |
op_collection_id |
ftulundlup |
language |
English |
topic |
Environmental Health and Occupational Health Air pollution Alzheimer's disease dementia particulate air pollution PM |
spellingShingle |
Environmental Health and Occupational Health Air pollution Alzheimer's disease dementia particulate air pollution PM Aström, Daniel Oudin Adolfsson, Rolf Segersson, David Forsberg, Bertil Oudin, Anna Local Contrasts in Concentration of Ambient Particulate Air Pollution (PM2.5) and Incidence of Alzheimer's Disease and Dementia : Results from the Betula Cohort in Northern Sweden |
topic_facet |
Environmental Health and Occupational Health Air pollution Alzheimer's disease dementia particulate air pollution PM |
description |
Exposure to fine particulate air pollution (PM2.5) is emerging as a risk factor for Alzheimer's disease (AD), but existing studies are still limited and heterogeneous. We have previously studied the association between dementia (AD and vascular dementia) and PM2.5 stemming from vehicle exhaust and wood-smoke in the Betula cohort in Northern Sweden. The aim of this commentary is to estimate the association between total PM2.5 and dementia in the Betula cohort, which is more relevant to include in future meta-estimates than the source-specific estimates. The hazard ratio for incident dementia associated with a 1µg/m3 increase in local PM2.5 was 1.38 (95% confidence interval: 0.99 -1.92). The interpretation of our results is that they indicate an association between local contrasts in concentration of PM2.5 at the residential address and incidence of dementia in a low-level setting. |
format |
Article in Journal/Newspaper |
author |
Aström, Daniel Oudin Adolfsson, Rolf Segersson, David Forsberg, Bertil Oudin, Anna |
author_facet |
Aström, Daniel Oudin Adolfsson, Rolf Segersson, David Forsberg, Bertil Oudin, Anna |
author_sort |
Aström, Daniel Oudin |
title |
Local Contrasts in Concentration of Ambient Particulate Air Pollution (PM2.5) and Incidence of Alzheimer's Disease and Dementia : Results from the Betula Cohort in Northern Sweden |
title_short |
Local Contrasts in Concentration of Ambient Particulate Air Pollution (PM2.5) and Incidence of Alzheimer's Disease and Dementia : Results from the Betula Cohort in Northern Sweden |
title_full |
Local Contrasts in Concentration of Ambient Particulate Air Pollution (PM2.5) and Incidence of Alzheimer's Disease and Dementia : Results from the Betula Cohort in Northern Sweden |
title_fullStr |
Local Contrasts in Concentration of Ambient Particulate Air Pollution (PM2.5) and Incidence of Alzheimer's Disease and Dementia : Results from the Betula Cohort in Northern Sweden |
title_full_unstemmed |
Local Contrasts in Concentration of Ambient Particulate Air Pollution (PM2.5) and Incidence of Alzheimer's Disease and Dementia : Results from the Betula Cohort in Northern Sweden |
title_sort |
local contrasts in concentration of ambient particulate air pollution (pm2.5) and incidence of alzheimer's disease and dementia : results from the betula cohort in northern sweden |
publisher |
IOS Press |
publishDate |
2021 |
url |
https://lup.lub.lu.se/record/9f4758c7-29f9-4de1-b5ee-01a67a544c22 https://doi.org/10.3233/JAD-201538 |
genre |
Northern Sweden |
genre_facet |
Northern Sweden |
op_source |
Journal of Alzheimer's Disease; 81(1), pp 83-85 (2021) ISSN: 1387-2877 |
op_relation |
https://lup.lub.lu.se/record/9f4758c7-29f9-4de1-b5ee-01a67a544c22 http://dx.doi.org/10.3233/JAD-201538 scopus:85105728122 pmid:33749652 |
op_doi |
https://doi.org/10.3233/JAD-201538 |
container_title |
Journal of Alzheimer's Disease |
container_volume |
81 |
container_issue |
1 |
container_start_page |
83 |
op_container_end_page |
85 |
_version_ |
1799486207883739136 |