Lipase-catalyzed synthesis of glycerol carbonate from renewable glycerol and dimethyl carbonate through transesterification
Glycerol carbonate is a key multifunctional compound employed as solvent, additive, monomer, and chemical intermediate. Enzymatic synthesis of glycerol carbonate from renewable starting materials (glycerol and dimethyl carbonate) was successfully achieved by-immobilized lipase from Candida antarctic...
Published in: | Journal of Molecular Catalysis B: Enzymatic |
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Main Authors: | , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
ELSEVIER SCIENCE BV
2016
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Subjects: | |
Online Access: | https://scholarworks.unist.ac.kr/handle/201301/20395 http://www.sciencedirect.com/science/article/pii/S1381117707001622 https://doi.org/10.1016/j.molcatb.2007.08.007 |
Summary: | Glycerol carbonate is a key multifunctional compound employed as solvent, additive, monomer, and chemical intermediate. Enzymatic synthesis of glycerol carbonate from renewable starting materials (glycerol and dimethyl carbonate) was successfully achieved by-immobilized lipase from Candida antarctica (CALB, Novozym 435). Addition of molecular sieves as scavenger for the removal of methanol, which was generated from dimethyl carbonate during the reaction, accelerated a reaction rate. After the optimization, the equimolar use of glycerol and dimethyl carbonate in the Novozym 435-catalyzed reaction yielded a glycerol carbonate with almost quantitative yield. The resulting glycerol carbonate from 60 degrees C reaction has shown the low enantiomeric excess (13% ee) as configuration of (R)-enantiomer. close |
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