Mannose-binding lectin genotypes and susceptibility to Epstein-Barr virus infection in infancy

In a cohort study in children <4 years of age in Greenland MBL2 genotypes and EBV antibody levels were determined. EBV seropositivity was significantly lower and time to seroconversion increased in MBL insufficient compared with MBL sufficient children, indicating that MBL may be involved in prim...

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Bibliographic Details
Published in:Clinical and Vaccine Immunology
Main Authors: Friborg, J.T., Jarrett, R., Koch, A., Garred, P., Freeland, J.M., Andersen, A., Melbye, M.
Format: Article in Journal/Newspaper
Language:unknown
Published: 2010
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Online Access:http://eprints.gla.ac.uk/36048/
Description
Summary:In a cohort study in children <4 years of age in Greenland MBL2 genotypes and EBV antibody levels were determined. EBV seropositivity was significantly lower and time to seroconversion increased in MBL insufficient compared with MBL sufficient children, indicating that MBL may be involved in primary EBV infection in infancy