The insulin-like growth factor system and colorectal cancer: clinical and experimental evidence
Objective: The aim of this review is to clarify the involvement of the insulinlike growth factor (IGF) system in the development of colorectal malignancy. Materials and methods: Medline searches were used to identify key articles relating the IGF system with the development of colorectal cancer. Res...
| Main Authors: | , , , |
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| Format: | Article in Journal/Newspaper |
| Language: | unknown |
| Published: |
SPRINGER
2006
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| Subjects: | |
| Online Access: | http://discovery.ucl.ac.uk/1315682/ |
| _version_ | 1821663433784819712 |
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| author | Davies, M Gupta, S Goldspink, G Winslet, M |
| author_facet | Davies, M Gupta, S Goldspink, G Winslet, M |
| author_sort | Davies, M |
| collection | University College London: UCL Discovery |
| description | Objective: The aim of this review is to clarify the involvement of the insulinlike growth factor (IGF) system in the development of colorectal malignancy. Materials and methods: Medline searches were used to identify key articles relating the IGF system with the development of colorectal cancer. Results: The IGF system has been linked to colorectal malignancy by a convergence of data from epidemiological, clinical and laboratory-based sources. Conclusion: Further work is needed to characterise the IGF system expression in the colon. Such clarification could lead to the identification of targets that can be manipulated for clinical advantage. |
| format | Article in Journal/Newspaper |
| genre | Northern Sweden |
| genre_facet | Northern Sweden |
| id | ftucl:oai:eprints.ucl.ac.uk.OAI2:1315682 |
| institution | Open Polar |
| language | unknown |
| op_collection_id | ftucl |
| op_source | INT J COLORECTAL DIS , 21 (3) 201 - 208. (2006) |
| publishDate | 2006 |
| publisher | SPRINGER |
| record_format | openpolar |
| spelling | ftucl:oai:eprints.ucl.ac.uk.OAI2:1315682 2025-01-16T23:55:10+00:00 The insulin-like growth factor system and colorectal cancer: clinical and experimental evidence Davies, M Gupta, S Goldspink, G Winslet, M 2006-04 http://discovery.ucl.ac.uk/1315682/ unknown SPRINGER INT J COLORECTAL DIS , 21 (3) 201 - 208. (2006) FACTOR-I RECEPTOR HUMAN COLON-CANCER FACTOR-BINDING-PROTEINS NECROSIS-FACTOR-ALPHA IGF-I FACTOR BINDING-PROTEIN-3 CHROMOSOME FRAGILITY FACTOR EXPRESSION NORTHERN SWEDEN BREAST-CANCER Article 2006 ftucl 2013-11-10T04:33:06Z Objective: The aim of this review is to clarify the involvement of the insulinlike growth factor (IGF) system in the development of colorectal malignancy. Materials and methods: Medline searches were used to identify key articles relating the IGF system with the development of colorectal cancer. Results: The IGF system has been linked to colorectal malignancy by a convergence of data from epidemiological, clinical and laboratory-based sources. Conclusion: Further work is needed to characterise the IGF system expression in the colon. Such clarification could lead to the identification of targets that can be manipulated for clinical advantage. Article in Journal/Newspaper Northern Sweden University College London: UCL Discovery |
| spellingShingle | FACTOR-I RECEPTOR HUMAN COLON-CANCER FACTOR-BINDING-PROTEINS NECROSIS-FACTOR-ALPHA IGF-I FACTOR BINDING-PROTEIN-3 CHROMOSOME FRAGILITY FACTOR EXPRESSION NORTHERN SWEDEN BREAST-CANCER Davies, M Gupta, S Goldspink, G Winslet, M The insulin-like growth factor system and colorectal cancer: clinical and experimental evidence |
| title | The insulin-like growth factor system and colorectal cancer: clinical and experimental evidence |
| title_full | The insulin-like growth factor system and colorectal cancer: clinical and experimental evidence |
| title_fullStr | The insulin-like growth factor system and colorectal cancer: clinical and experimental evidence |
| title_full_unstemmed | The insulin-like growth factor system and colorectal cancer: clinical and experimental evidence |
| title_short | The insulin-like growth factor system and colorectal cancer: clinical and experimental evidence |
| title_sort | insulin-like growth factor system and colorectal cancer: clinical and experimental evidence |
| topic | FACTOR-I RECEPTOR HUMAN COLON-CANCER FACTOR-BINDING-PROTEINS NECROSIS-FACTOR-ALPHA IGF-I FACTOR BINDING-PROTEIN-3 CHROMOSOME FRAGILITY FACTOR EXPRESSION NORTHERN SWEDEN BREAST-CANCER |
| topic_facet | FACTOR-I RECEPTOR HUMAN COLON-CANCER FACTOR-BINDING-PROTEINS NECROSIS-FACTOR-ALPHA IGF-I FACTOR BINDING-PROTEIN-3 CHROMOSOME FRAGILITY FACTOR EXPRESSION NORTHERN SWEDEN BREAST-CANCER |
| url | http://discovery.ucl.ac.uk/1315682/ |