Synthesis of (S)-(+)-cericlamine through lipase-catalyzed aminolysis of azo acetates

Prechter A, Gröger H, Heinrich MR. Synthesis of (S)-(+)-cericlamine through lipase-catalyzed aminolysis of azo acetates. Organic & Biomolecular Chemistry . 2012;10(17): 3384. The kinetic enzymatic resolution of azo acetates via aminolysis with Candida antarctica lipase B has been investigated us...

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Published in:Organic & Biomolecular Chemistry
Main Authors: Prechter, Agnes, Gröger, Harald, Heinrich, Markus R
Format: Article in Journal/Newspaper
Language:English
Published: Royal Society of Chemistry (RSC) 2012
Subjects:
Antarc*
Antarctica
Online Access:https://pub.uni-bielefeld.de/record/2490875
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spelling ftubbiepub:oai:pub.uni-bielefeld.de:2490875 2023-05-15T13:40:40+02:00 Synthesis of (S)-(+)-cericlamine through lipase-catalyzed aminolysis of azo acetates Prechter, Agnes Gröger, Harald Heinrich, Markus R 2012 https://pub.uni-bielefeld.de/record/2490875 eng eng Royal Society of Chemistry (RSC) info:eu-repo/semantics/altIdentifier/doi/10.1039/c2ob25247c info:eu-repo/semantics/altIdentifier/issn/1477-0520 info:eu-repo/semantics/altIdentifier/issn/1477-0539 info:eu-repo/semantics/altIdentifier/wos/000302420700003 info:eu-repo/semantics/altIdentifier/pmid/22441297 https://pub.uni-bielefeld.de/record/2490875 info:eu-repo/semantics/closedAccess http://purl.org/coar/resource_type/c_6501 info:eu-repo/semantics/article doc-type:article text 2012 ftubbiepub https://doi.org/10.1039/c2ob25247c 2022-02-08T22:32:46Z Prechter A, Gröger H, Heinrich MR. Synthesis of (S)-(+)-cericlamine through lipase-catalyzed aminolysis of azo acetates. Organic & Biomolecular Chemistry . 2012;10(17): 3384. The kinetic enzymatic resolution of azo acetates via aminolysis with Candida antarctica lipase B has been investigated using benzylamine as amine component. The products obtained from this biotransformation in high enantiomeric purity can serve as valuable precursors for various amino alcohols, as exemplified by the synthesis of the serotonin reuptake inhibitor (S)-(+)-cericlamine. Article in Journal/Newspaper Antarc* Antarctica PUB - Publications at Bielefeld University Organic & Biomolecular Chemistry 10 17 3384
institution Open Polar
collection PUB - Publications at Bielefeld University
op_collection_id ftubbiepub
language English
description Prechter A, Gröger H, Heinrich MR. Synthesis of (S)-(+)-cericlamine through lipase-catalyzed aminolysis of azo acetates. Organic & Biomolecular Chemistry . 2012;10(17): 3384. The kinetic enzymatic resolution of azo acetates via aminolysis with Candida antarctica lipase B has been investigated using benzylamine as amine component. The products obtained from this biotransformation in high enantiomeric purity can serve as valuable precursors for various amino alcohols, as exemplified by the synthesis of the serotonin reuptake inhibitor (S)-(+)-cericlamine.
format Article in Journal/Newspaper
author Prechter, Agnes
Gröger, Harald
Heinrich, Markus R
spellingShingle Prechter, Agnes
Gröger, Harald
Heinrich, Markus R
Synthesis of (S)-(+)-cericlamine through lipase-catalyzed aminolysis of azo acetates
author_facet Prechter, Agnes
Gröger, Harald
Heinrich, Markus R
author_sort Prechter, Agnes
title Synthesis of (S)-(+)-cericlamine through lipase-catalyzed aminolysis of azo acetates
title_short Synthesis of (S)-(+)-cericlamine through lipase-catalyzed aminolysis of azo acetates
title_full Synthesis of (S)-(+)-cericlamine through lipase-catalyzed aminolysis of azo acetates
title_fullStr Synthesis of (S)-(+)-cericlamine through lipase-catalyzed aminolysis of azo acetates
title_full_unstemmed Synthesis of (S)-(+)-cericlamine through lipase-catalyzed aminolysis of azo acetates
title_sort synthesis of (s)-(+)-cericlamine through lipase-catalyzed aminolysis of azo acetates
publisher Royal Society of Chemistry (RSC)
publishDate 2012
url https://pub.uni-bielefeld.de/record/2490875
genre Antarc*
Antarctica
genre_facet Antarc*
Antarctica
op_relation info:eu-repo/semantics/altIdentifier/doi/10.1039/c2ob25247c
info:eu-repo/semantics/altIdentifier/issn/1477-0520
info:eu-repo/semantics/altIdentifier/issn/1477-0539
info:eu-repo/semantics/altIdentifier/wos/000302420700003
info:eu-repo/semantics/altIdentifier/pmid/22441297
https://pub.uni-bielefeld.de/record/2490875
op_rights info:eu-repo/semantics/closedAccess
op_doi https://doi.org/10.1039/c2ob25247c
container_title Organic & Biomolecular Chemistry
container_volume 10
container_issue 17
container_start_page 3384
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