The importance of environment on respiratory genotype/phenotype relationships in the Inuit

Genetic and environmental influences and their interactions are central to asthma pathogenesis. This study aimed to investigate the effects of different macro-environments on asthma genotype-phenotype associations in two geographically separated populations with common ancestry.

Bibliographic Details
Published in:Allergy
Main Authors: Candelaria, P V, Backer, Vibeke, Khoo, S-K, Bizzintino, J A, Hayden, C M, Baynam, G, Laing, I A, Zhang, G, Porsbjerg, Celeste Michala, Goldblatt, J, Le Souëf, P N, Bjerregaard, Peter
Format: Article in Journal/Newspaper
Language:English
Published: 2010
Subjects:
Adult
Asthma
Denmark
Female
Gene Frequency
Genetic Association Studies
Genetics
Population
Genotype
Greenland
Humans
Inuits
Male
Phenotype
Sex Factors
inuit
inuits
Online Access:https://portal.findresearcher.sdu.dk/da/publications/dd18717f-7ea9-4936-8561-53b36f1d9ff8
https://doi.org/10.1111/j.1398-9995.2009.02145.x
Description
Summary:Genetic and environmental influences and their interactions are central to asthma pathogenesis. This study aimed to investigate the effects of different macro-environments on asthma genotype-phenotype associations in two geographically separated populations with common ancestry.

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