Prevalence and incidence of Parkinson's disease in The Faroe Islands
Udgivelsesdato: 2008-August Objective - A study in The Faroe Islands in 1995 suggested a high prevalence of idiopathic Parkinson's disease (IPD) and total parkinsonism of 187.6 and 233.4 per 100,000 inhabitants respectively. Methods - Detailed case-finding methods 10 years later were used and a...
| Published in: | Acta Neurologica Scandinavica |
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| Main Authors: | , , , , , |
| Format: | Article in Journal/Newspaper |
| Language: | English |
| Published: |
2008
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| Subjects: | |
| Online Access: | https://portal.findresearcher.sdu.dk/da/publications/d4f86c70-78e4-11dd-bead-000ea68e967b https://doi.org/10.1111/j.1600-0404.2007.00991.x https://findresearcher.sdu.dk/ws/files/34993642/grandjean_prevalence_2008.doc |
| Summary: | Udgivelsesdato: 2008-August Objective - A study in The Faroe Islands in 1995 suggested a high prevalence of idiopathic Parkinson's disease (IPD) and total parkinsonism of 187.6 and 233.4 per 100,000 inhabitants respectively. Methods - Detailed case-finding methods 10 years later were used and a neurologist has verified the diagnosis. Results - The crude prevalence of IPD and total parkinsonism was 206.7 per 100,000 and 227.4 per 100,000 respectively. The age-adjusted prevalence is twice as high as data from Norway and Denmark. Age at initiation of treatment and the fatality rate did not explain the increased prevalence. During 1995-2005, the average annual incidence was 21.1 per 100,000 persons for Parkinson's disease, and 22.9 per 100,000 persons, if including atypical parkinsonism. Conclusion - The high prevalence was verified and linked to a high incidence. The cause of the high prevalence is unknown, but neurotoxic contaminants in traditional food may play a role in the pathogenesis in this population, perhaps jointly with genetic predisposition. |
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