Effect of sex, age, and race on the clinical presentation of tuberculosis: a 15-year population-based study

Extrapulmonary tuberculosis (EPTB) is an important health problem that may cause serious morbidity and diagnostic challenges. We conducted a case-control study involving 5,684, approximately 99% of bacteriologically confirmed TB patients (including 1,925 EPTB cases) diagnosed in Denmark and Greenlan...

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Bibliographic Details
Published in:The American Journal of Tropical Medicine and Hygiene
Main Authors: Zhang, Xinyu, Bengård Andersen, Åse, Lillebaek, Troels, Kamper-Jørgensen, Zaza, Thomsen, Vibeke Østergaard, Ladefoged, Karin, Marrs, Carl F, Zhang, Lixin, Yang, Zhenhua
Format: Article in Journal/Newspaper
Language:English
Published: 2011
Subjects:
Adolescent
Adult
Aged
80 and over
Aging
Continental Population Groups
Disease Susceptibility
Female
Humans
Male
Middle Aged
Risk Factors
Sex Characteristics
Tuberculosis
Young Adult
Greenland
Online Access:https://portal.findresearcher.sdu.dk/da/publications/048c29ea-a3d1-4f1a-932c-5534f880cb6e
https://doi.org/10.4269/ajtmh.2011.10-0630
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Summary:Extrapulmonary tuberculosis (EPTB) is an important health problem that may cause serious morbidity and diagnostic challenges. We conducted a case-control study involving 5,684, approximately 99% of bacteriologically confirmed TB patients (including 1,925 EPTB cases) diagnosed in Denmark and Greenland during 1992-2007 to gain insight to the role of host factors in EPTB pathogenesis. Among patients from Somalia and Asia, persons 25-44 and 45-64 years of age were more likely to have EPTB than persons 15-24 years of age. In contrast, among persons from Greenland, the two oldest age groups were significantly less likely to have EPTB than the youngest age group. For all the age groups, the odds for having EPTB was significantly higher among patients from Somalia and Asia and significantly lower among the patients from Greenland than among patients from Denmark. Furthermore, the occurrence of specific types of EPTB significantly varied among different age groups or origins.

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