The isolation of (6S, 9S)-cyclo(prolylvalyl) from marine actinomycete, by use of high speed countercurrent chromatography

The marine actinomycete B 1758 came from the actinomycete collection of the Alfred Wegener Institute for Polar and Marine Research in Bremerhafen, Germany. 1.079 g of raw extract was obtained by fermentation. Seven fractions were separated by column chromatography on silica gel. Fraction 4 was separ...

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Bibliographic Details
Main Authors: Smelcerovic, Andrija, Schiebel, Mirko, Djordjevic, Sinisa
Format: Article in Journal/Newspaper
Language:English
Published: 2002
Subjects:
543
547
575
Online Access:https://resolver.sub.uni-goettingen.de/purl?gro-2/61122
https://resolver.sub.uni-goettingen.de/purl?gs-1/4449
Description
Summary:The marine actinomycete B 1758 came from the actinomycete collection of the Alfred Wegener Institute for Polar and Marine Research in Bremerhafen, Germany. 1.079 g of raw extract was obtained by fermentation. Seven fractions were separated by column chromatography on silica gel. Fraction 4 was separated by high speed countercurrent chromatography. Fraction 4.6 yielded 5.2 mg of (6S, 9S)-cyclo(prolylvalyl). Keywords: (6S 9S)-cyclo(prolylvalyl) marine actinomycete B 1758 HSCCC