The faroes statement : human health effects of developmental exposure to chemicals in our environment.

• Published in: Basic & Clinical Pharmacology & Toxicology
• Main Authors: Grandjean, Philippe, Bellinger, David, Bergman, Åke, Cordier, Sylvaine, Davey-Smith, George, Eskenazi, Brenda, Gee, David, Gray, Kimberly, Hanson, Mark, van den Hazel, Peter, Heindel, Jerrold J, Heinzow, Birger, Hertz-Picciotto, Irva, Hu, Howard, Huang, Terry T-K, Jensen, Tina Kold, Landrigan, Philip J, McMillen, I Caroline, Murata, Katsuyuki, Ritz, Beate, Schoeters, Greet, Skakkebaek, Niels Erik, Skerfving, Staffan, Weihe, Pal
• Format: Article in Journal/Newspaper
• Language: English
• Published: Avdelningen för miljökemi 2008
• Subjects: Animals; Child Development/drug effects; Embryonic Development/drug effects; Environmental Exposure/*adverse effects; Environmental Pollutants/*toxicity; Female; Fetal Development/drug effects; Gene Expression/drug effects; Humans; Infant; Newborn; Maternal-Fetal Exchange; Pregnancy; Prenatal Exposure Delayed Effects; Chemical Sciences; Kemi; Environmental Sciences; Miljövetenskap; Tórshavn; Faroes
• Online Access: http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-13274; https://doi.org/10.1111/j.1742-7843.2007.00114.x

The periods of embryonic, foetal and infant developmentare remarkably susceptible to environmental hazards. Toxicexposures to chemical pollutants during these windows ofincreased susceptibility can cause disease and disability ininfants, children and across the entire span of human life.Among the effects of toxic exposures recognized in the pasthave been spontaneous abortion, congenital malformations,lowered birthweight and other adverse effects. These outcomesmay be readily apparent. However, even subtle changes causedby chemical exposures during early development may leadto important functional deficits and increased risks ofdisease later in life. The timing of exposure during early lifehas therefore become a crucial factor to be considered intoxicological assessments.During 20–24 May 2007, researchers in the fields of environmentalhealth, environmental chemistry, developmentalbiology, toxicology, epidemiology, nutrition and paediatricsgathered at the International Conference on Fetal Programmingand Developmental Toxicity, in Tórshavn, FaroeIslands. The conference goal was to highlight new insightsinto the effects of prenatal and early postnatal exposure tochemical agents, and their sustained effects on the individualthroughout the lifespan. The conference brought togetherresearchers to focus on human data and the translationof laboratory results to elucidate the environmental risks tohuman health.