IgE sero-positivity to 27 Culicoides recombinant (r-) allergens.

• Main Authors: Jasmin Birras (11707271), Samuel J. White (10512181), Sigridur Jonsdottir (1303788), Ella N. Novotny (11707274), Anja Ziegler (11707277), A. Douglas Wilson (11707280), Rebecka Frey (3362939), Sigurbjörg Torsteinsdottir (11707283), Marcos Alcocer (8212260), Eliane Marti (157764)
• Format: Still Image
• Language: unknown
• Published: 2021
• Subjects: Biochemistry; Medicine; Microbiology; Cell Biology; Genetics; Molecular Biology; Neuroscience; Biotechnology; Evolutionary Biology; Immunology; Developmental Biology; Cancer; Infectious Diseases; Virology; primary sensitizing allergen; mediated allergic dermatitis; insect bite hypersensitivity; first clinical signs; first clinical expression; 110 serological samples; 0 &# 8211; significantly affect degree; 4 &# 8211; icelandic horses residing; subsequently developed ibh; ibh (& lt; ige microarray profiling; >- specific ige; significantly higher degree; culicoides spp </; affected horses exported; significantly higher; culicoides </; horses exported; 4 years; horses incited; horses imported; ige levels; significant increase; positivity rates; natural course; high prevalence; comprehensive panel; causative agents; 7 years; 23 ); 21 ); 16 ); Iceland
• Online Access: https://doi.org/10.1371/journal.pone.0257819.g001

Percentage of horses with IgE levels above the cut-off values (as indicated in Table 2 ) in horses exported from Iceland to Switzerland that developed insect bite hypersensitivity (IBH; n = 59) or remained healthy (H; n = 51), and in horses living in Iceland (unexposed; n = 22). Serum samples were taken the summer of clinical onset of IBH (T IBH ) and at the corresponding time in the H group. The allergens are listed in decreasing order from those binding serum IgE in the highest number of horses at time of clinical onset of IBH (T IBH ). P values were calculated with the Fisher’s exact test and Bonferroni correction done for multiple comparisons. ** IBH significantly different from H and unexposed (cP <0.05). * IBH significantly different from H (cP<0.05). No significant differences between H and unexposed for any r-allergen.