Principal component analyses of progressively filtered off-target SNP datasets.

• Main Authors: Tristan M. Baecklund (10573715), Michael E. Donaldson (4431115), Karsten Hueffer (606200), Christopher J. Kyle (8136867)
• Format: Still Image
• Language: unknown
• Published: 2021
• Subjects: Genetics; Evolutionary Biology; Ecology; Infectious Diseases; Environmental Sciences not elsewhere classified; Biological Sciences not elsewhere classified; somewhat unexpected given; rapidly changing environments; north american range; necessarily reflect causation; corroborating past research; undermine local adaptation; local adaptation enhance; contrasting genetic structure; mediate host responses; provide data relevant; div >< p; neutral genetic structure; arctic rabies variants; local adaptation; genetic structure; neutral loci; primary host; natural host; host populations; traits expected; sequencing assay; sampled regions; remains unknown; outliers associated; northern climates; lived nature; largely persists; increased frequencies; geographic distributions; foxes predominated; evolutionary relationships; dispersal capacities; direct link; differential selection; data contribute; assessed correlations; arctic rabies; arctic fox; advantageous genotypes; Arctic; Arctic Fox; Arviat; Victoria Island
• Online Access: https://doi.org/10.1371/journal.pone.0258975.s001

Clustering of the 96 arctic fox samples based on on-target SNPs throughout filtering steps. a) PCA of all off-target SNPs after filtering for MAF, missing-data, and biallelic SNPs (n = 6432) and b) PCA of all identified off-target SNPs after analysis with Variant Effect Predictor and prior to linkage pruning (n = 283). Arviat = black square; Chevak = yellow circle; Hooper Bay = blue triangle; Victoria Island = green diamond. (TIF)