Creatine kinase is associated with reduced inflammation in a general population: The Tromsø study

Background: Creatine kinase (CK) has been associated with reduced inflammation in obesity while inflammation is associated with obesity-related cardiovascular diseases. We investigated the relationship between CK and high sensitive C-reactive protein (hs-CRP) in a general population. Methods: CK and...

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Main Authors: Svein Ivar Bekkelund, Stein Harald Johnsen
Format: Article in Journal/Newspaper
Language:unknown
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Online Access:https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0198133
https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0198133&type=printable
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Summary:Background: Creatine kinase (CK) has been associated with reduced inflammation in obesity while inflammation is associated with obesity-related cardiovascular diseases. We investigated the relationship between CK and high sensitive C-reactive protein (hs-CRP) in a general population. Methods: CK and hs-CRP were measured in the population-based Tromsø study that included entire birth cohorts and random samples of citizens between 30–87 years of age. The analyses were performed sex-stratified in 5969 men and 6827 women. Results: CK correlated negatively with hs-CRP in men (r = -0.08, P