Biomonitoring of polybrominated diphenyl ether (PBDE) pollution: A field study

• Published in: Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology
• Main Authors: Mariottini, Michela, Corsi, Ilaria, Della Torre, Camilla, Caruso, Tancredi, Bianchini, Aldo, Nesi, Ilaria, Focardi, Silvia
• Format: Article in Journal/Newspaper
• Language: English
• Published: 2008
• Subjects: DIBENZO-P-DIOXINS; cytochrome P450; CARP CYPRINUS-CARPIO; biomarkers; EEL ANGUILLA-ANGUILLA; ORBETELLO LAGOON; Anguilla anguilla; BIOMARKER RESPONSES; ARYL-HYDROCARBON RECEPTOR; PBDEs; ENDOCRINE DISRUPTORS; Mediterranean lagoon; PESTICIDE RISK-ASSESSMENT; POLYCHLORINATED NAPHTHALENES; BROMINATED FLAME RETARDANTS
• Online Access: https://pure.qub.ac.uk/en/publications/e54c40c6-1746-4eef-a6c5-e2c63b24f3e6; https://doi.org/10.1016/j.cbpc.2008.03.011

Polybrominated diphenyl ethers (PBDEs) and cytochrome P450 enzyme activities were investigated in European eels (Anguilla anguilla) collected from seven sites in a coastal lagoon in the north-western Mediterranean Sea, Orbetello lagoon (Italy). Twelve PBDE congeners were measured in muscle and two CYP1A enzyme activities, 7-ethoxyresorufin-O-deethylase (EROD) and benzo(a)pyrene monooxygenase (BP (a)PMO), were investigated in liver microsomal fraction in order to obtain insights into the health of the lagoon environment. PBDE muscle levels were low and the most abundant congeners were 2,2',4,4'-tetrabronnodiphenylether (BDE-47), 2,2',4,4',5,5'-hexaBDE (BDE-153) and 2,2',4,5'-tetraBDE (BDE-49). EROD and B(a)PMO activities were also low and no differences were observed between eels from different sites. Multivariate analysis (PCA) did not indicate correlations between PBDEs and either P450 activities. (c) 2008 Elsevier Inc. All rights reserved.