Biomonitoring of polybrominated diphenyl ether (PBDE) pollution: A field study

Polybrominated diphenyl ethers (PBDEs) and cytochrome P450 enzyme activities were investigated in European eels (Anguilla anguilla) collected from seven sites in a coastal lagoon in the north-western Mediterranean Sea, Orbetello lagoon (Italy). Twelve PBDE congeners were measured in muscle and two C...

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Bibliographic Details
Published in:Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology
Main Authors: Mariottini, Michela, Corsi, Ilaria, Della Torre, Camilla, Caruso, Tancredi, Bianchini, Aldo, Nesi, Ilaria, Focardi, Silvia
Format: Article in Journal/Newspaper
Language:English
Published: 2008
Subjects:
DIBENZO-P-DIOXINS
cytochrome P450
CARP CYPRINUS-CARPIO
biomarkers
EEL ANGUILLA-ANGUILLA
ORBETELLO LAGOON
Anguilla anguilla
BIOMARKER RESPONSES
ARYL-HYDROCARBON RECEPTOR
PBDEs
ENDOCRINE DISRUPTORS
Mediterranean lagoon
PESTICIDE RISK-ASSESSMENT
POLYCHLORINATED NAPHTHALENES
BROMINATED FLAME RETARDANTS
Online Access:https://pure.qub.ac.uk/en/publications/e54c40c6-1746-4eef-a6c5-e2c63b24f3e6
https://doi.org/10.1016/j.cbpc.2008.03.011
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Summary:Polybrominated diphenyl ethers (PBDEs) and cytochrome P450 enzyme activities were investigated in European eels (Anguilla anguilla) collected from seven sites in a coastal lagoon in the north-western Mediterranean Sea, Orbetello lagoon (Italy). Twelve PBDE congeners were measured in muscle and two CYP1A enzyme activities, 7-ethoxyresorufin-O-deethylase (EROD) and benzo(a)pyrene monooxygenase (BP (a)PMO), were investigated in liver microsomal fraction in order to obtain insights into the health of the lagoon environment. PBDE muscle levels were low and the most abundant congeners were 2,2',4,4'-tetrabronnodiphenylether (BDE-47), 2,2',4,4',5,5'-hexaBDE (BDE-153) and 2,2',4,5'-tetraBDE (BDE-49). EROD and B(a)PMO activities were also low and no differences were observed between eels from different sites. Multivariate analysis (PCA) did not indicate correlations between PBDEs and either P450 activities. (c) 2008 Elsevier Inc. All rights reserved.

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