First report of successful isolation of a HPR0‐like variant of the infectious salmon anaemia virus (ISAV) using cell culture
ISAV is the causative agent of the infectious salmon anaemia (ISA), a disease listed by the OIE that has caused important economic losses to the Atlantic salmon (Salmo salar) industry. ISAV variants are identified as pathogenic or non‐pathogenic based on the presence or absence of a deletion in the...
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Online Access: | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299946/ http://www.ncbi.nlm.nih.gov/pubmed/34843624 https://doi.org/10.1111/jfd.13556 |
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ftpubmed:oai:pubmedcentral.nih.gov:9299946 2023-05-15T15:32:07+02:00 First report of successful isolation of a HPR0‐like variant of the infectious salmon anaemia virus (ISAV) using cell culture Ditlecadet, D. Gautreau, C. Boston, L. Liston, R. Johnsen, E. Gagné, N. 2021-11-29 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299946/ http://www.ncbi.nlm.nih.gov/pubmed/34843624 https://doi.org/10.1111/jfd.13556 en eng John Wiley and Sons Inc. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299946/ http://www.ncbi.nlm.nih.gov/pubmed/34843624 http://dx.doi.org/10.1111/jfd.13556 © 2021 Her Majesty the Queen in Right of Canada. Journal of Fish Diseases published by John Wiley & Sons Ltd. Reproduced with the permission of the Minister of Fisheries and Oceans Canada. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. CC-BY-NC-ND J Fish Dis Short Communications Text 2021 ftpubmed https://doi.org/10.1111/jfd.13556 2022-07-31T02:20:57Z ISAV is the causative agent of the infectious salmon anaemia (ISA), a disease listed by the OIE that has caused important economic losses to the Atlantic salmon (Salmo salar) industry. ISAV variants are identified as pathogenic or non‐pathogenic based on the presence or absence of a deletion in the highly polymorphic region (HPR) of segment 6 (S6). HPRΔ variants (pathogenic) are the only forms of the virus known to grow in cell culture. This is the first report of a HPR0 variant isolated in cell culture. The isolate is, however, atypical as it shows a marker of virulent variants on another segment (S5), which has never been reported for any other HPR0 variants. The significance of this finding remains unclear until more in‐depth work is carried out but does challenge current knowledge. Text Atlantic salmon Salmo salar PubMed Central (PMC) Journal of Fish Diseases 45 3 479 483 |
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Short Communications |
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Short Communications Ditlecadet, D. Gautreau, C. Boston, L. Liston, R. Johnsen, E. Gagné, N. First report of successful isolation of a HPR0‐like variant of the infectious salmon anaemia virus (ISAV) using cell culture |
topic_facet |
Short Communications |
description |
ISAV is the causative agent of the infectious salmon anaemia (ISA), a disease listed by the OIE that has caused important economic losses to the Atlantic salmon (Salmo salar) industry. ISAV variants are identified as pathogenic or non‐pathogenic based on the presence or absence of a deletion in the highly polymorphic region (HPR) of segment 6 (S6). HPRΔ variants (pathogenic) are the only forms of the virus known to grow in cell culture. This is the first report of a HPR0 variant isolated in cell culture. The isolate is, however, atypical as it shows a marker of virulent variants on another segment (S5), which has never been reported for any other HPR0 variants. The significance of this finding remains unclear until more in‐depth work is carried out but does challenge current knowledge. |
format |
Text |
author |
Ditlecadet, D. Gautreau, C. Boston, L. Liston, R. Johnsen, E. Gagné, N. |
author_facet |
Ditlecadet, D. Gautreau, C. Boston, L. Liston, R. Johnsen, E. Gagné, N. |
author_sort |
Ditlecadet, D. |
title |
First report of successful isolation of a HPR0‐like variant of the infectious salmon anaemia virus (ISAV) using cell culture |
title_short |
First report of successful isolation of a HPR0‐like variant of the infectious salmon anaemia virus (ISAV) using cell culture |
title_full |
First report of successful isolation of a HPR0‐like variant of the infectious salmon anaemia virus (ISAV) using cell culture |
title_fullStr |
First report of successful isolation of a HPR0‐like variant of the infectious salmon anaemia virus (ISAV) using cell culture |
title_full_unstemmed |
First report of successful isolation of a HPR0‐like variant of the infectious salmon anaemia virus (ISAV) using cell culture |
title_sort |
first report of successful isolation of a hpr0‐like variant of the infectious salmon anaemia virus (isav) using cell culture |
publisher |
John Wiley and Sons Inc. |
publishDate |
2021 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299946/ http://www.ncbi.nlm.nih.gov/pubmed/34843624 https://doi.org/10.1111/jfd.13556 |
genre |
Atlantic salmon Salmo salar |
genre_facet |
Atlantic salmon Salmo salar |
op_source |
J Fish Dis |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9299946/ http://www.ncbi.nlm.nih.gov/pubmed/34843624 http://dx.doi.org/10.1111/jfd.13556 |
op_rights |
© 2021 Her Majesty the Queen in Right of Canada. Journal of Fish Diseases published by John Wiley & Sons Ltd. Reproduced with the permission of the Minister of Fisheries and Oceans Canada. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
op_rightsnorm |
CC-BY-NC-ND |
op_doi |
https://doi.org/10.1111/jfd.13556 |
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Journal of Fish Diseases |
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45 |
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3 |
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479 |
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483 |
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1766362619088732160 |