Regional Patterns of Infant Mortality Caused by Lethal Congenital Anomalies

Purpose: To assess the regional patterns of infant mortality due to lethal congenital anomalies, and the potential reasons for the regional patterns. Method: The study analyzed 2,507 infant deaths due to lethal congenital anomalies among 1,178,452 live births in 9 of the 12 Canadian provinces and te...

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Bibliographic Details
Published in:Canadian Journal of Public Health
Main Authors: Wen, Shi Wu, Liu, Shiliang, Joseph, K. S., Trouton, Konia, Allen, Alexander
Format: Text
Language:English
Published: Springer International Publishing 1999
Subjects:
Online Access:http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6979681/
http://www.ncbi.nlm.nih.gov/pubmed/10570575
https://doi.org/10.1007/BF03404519
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Summary:Purpose: To assess the regional patterns of infant mortality due to lethal congenital anomalies, and the potential reasons for the regional patterns. Method: The study analyzed 2,507 infant deaths due to lethal congenital anomalies among 1,178,452 live births in 9 of the 12 Canadian provinces and territories from 1990 to 1995 recorded in Statistics Canada’s live birth and death data bases. Results: Compared with the province of Quebec, congenital anomaly-attributed infant mortality was higher in Newfoundland, Saskatchewan, and Alberta. These differences in infant mortality were substantial for cardiovascular system anomalies and especially anen-cephaly. For infant mortality due to chromosomal anomalies, however, there was little interprovincial variation. Conclusions: Despite substantial recent reductions in lethal congenital anomaly-attributed infant mortality, there remain major regional variations in infant mortality caused by certain forms of congenital anomalies including anen-cephaly and cardiovascular system anomalies.