Nonpharmacologic treatment of hypertriglyceridemia: Focus on fish oils

Early studies in Greenland Eskimos stimulated interest in evaluating the effect of Omega‐3 fatty acids on coronary artery disease. Subsequent studies showed a significant decrease in triglyceride levels in patients receiving high doses of fish oil containing DHA and EPA. Slight increases in LDL were...

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Bibliographic Details
Published in:Clinical Cardiology
Main Author: Harris, William S.
Format: Text
Language:English
Published: Wiley Periodicals, Inc. 2009
Subjects:
Articles
Greenland
Indian
eskimo*
Online Access:http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6655676/
http://www.ncbi.nlm.nih.gov/pubmed/10376196
https://doi.org/10.1002/clc.4960221408
Description
Summary:Early studies in Greenland Eskimos stimulated interest in evaluating the effect of Omega‐3 fatty acids on coronary artery disease. Subsequent studies showed a significant decrease in triglyceride levels in patients receiving high doses of fish oil containing DHA and EPA. Slight increases in LDL were also observed in patients receiving fish oil supplements. These studies have also shown a dose—response effect which persists as long as supplementation continues. Later trials, specifically the Diet and Reinfarction Trial and the Indian Experiment of Infarct Survival, have demonstrated a reduction in cardiac death rates and in the incidence of cardiac symptoms in patients receiving fish oil.

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