iDog: an integrated resource for domestic dogs and wild canids

The domestic dog (Canis lupus familiaris) is indisputably one of man's best friends. It is also a fundamental model for many heritable human diseases. Here, we present iDog (http://bigd.big.ac.cn/idog), the first integrated resource dedicated to domestic dogs and wild canids. It incorporates a...

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Bibliographic Details
Published in:Nucleic Acids Research
Main Authors: Tang, Bixia, Zhou, Qing, Dong, Lili, Li, Wulue, Zhang, Xiangquan, Lan, Li, Zhai, Shuang, Xiao, Jingfa, Zhang, Zhang, Bao, Yiming, Zhang, Ya-Ping, Wang, Guo-Dong, Zhao, Wenming
Format: Text
Language:English
Published: Oxford University Press 2019
Subjects:
Database Issue
Canis lupus
Online Access:http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323916/
http://www.ncbi.nlm.nih.gov/pubmed/30371881
https://doi.org/10.1093/nar/gky1041
Description
Summary:The domestic dog (Canis lupus familiaris) is indisputably one of man's best friends. It is also a fundamental model for many heritable human diseases. Here, we present iDog (http://bigd.big.ac.cn/idog), the first integrated resource dedicated to domestic dogs and wild canids. It incorporates a variety of omics data, including genome sequences assemblies for dhole and wolf, genomic variations extracted from hundreds of dog/wolf whole genomes, phenotype/disease traits curated from dog research communities and public resources, gene expression profiles derived from published RNA-Seq data, gene ontology for functional annotation, homolog gene information for multiple organisms and disease-related literature. Additionally, iDog integrates sequence alignment tools for data analyses and a genome browser for data visualization. iDog will not only benefit the global dog research community, but also provide access to a user-friendly consolidation of dog information to a large number of dog enthusiasts.

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