Neurophysiological signatures of Alzheimer’s disease and frontotemporal lobar degeneration: pathology versus phenotype

Sami et al. identify characteristic neurophysiological signatures of five neurodegenerative diseases, including two variants of Alzheimer’s disease and three forms of frontotemporal lobar degeneration. Disorders that share a common underlying pathology have a similar spectral signature of altered co...

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Bibliographic Details
Published in:Brain
Main Authors: Sami, Saber, Williams, Nitin, Hughes, Laura E, Cope, Thomas E, Rittman, Timothy, Coyle-Gilchrist, Ian T S, Henson, Richard N, Rowe, James B
Format: Text
Language:English
Published: Oxford University Press 2018
Subjects:
Online Access:http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061803/
http://www.ncbi.nlm.nih.gov/pubmed/30060017
https://doi.org/10.1093/brain/awy180
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Summary:Sami et al. identify characteristic neurophysiological signatures of five neurodegenerative diseases, including two variants of Alzheimer’s disease and three forms of frontotemporal lobar degeneration. Disorders that share a common underlying pathology have a similar spectral signature of altered connectivity, regardless of phenotype.