The Relationship between Persistent Organic Pollutants Exposure and Type 2 Diabetes among First Nations in Ontario and Manitoba, Canada: A Difference in Difference Analysis
We previously studied the association between fish consumption and prevalence of type 2 diabetes (T2D) in Manitoba and Ontario First Nations (FNs), Canada and found different results. In this study, we used a difference in difference model to analyze the data. Dietary and health data from the First...
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ftpubmed:oai:pubmedcentral.nih.gov:5877084 2023-05-15T16:15:20+02:00 The Relationship between Persistent Organic Pollutants Exposure and Type 2 Diabetes among First Nations in Ontario and Manitoba, Canada: A Difference in Difference Analysis Marushka, Lesya Hu, Xuefeng Batal, Malek Sadik, Tonio Schwartz, Harold Ing, Amy Fediuk, Karen Tikhonov, Constantine Chan, Hing Man 2018-03-17 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877084/ http://www.ncbi.nlm.nih.gov/pubmed/29562596 https://doi.org/10.3390/ijerph15030539 en eng MDPI http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877084/ http://www.ncbi.nlm.nih.gov/pubmed/29562596 http://dx.doi.org/10.3390/ijerph15030539 © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). CC-BY Article Text 2018 ftpubmed https://doi.org/10.3390/ijerph15030539 2018-04-22T01:03:10Z We previously studied the association between fish consumption and prevalence of type 2 diabetes (T2D) in Manitoba and Ontario First Nations (FNs), Canada and found different results. In this study, we used a difference in difference model to analyze the data. Dietary and health data from the First Nations Food Nutrition and Environment Study, a cross-sectional study of 706 Manitoba and 1429 Ontario FNs were analyzed. The consumption of fish was estimated using a food frequency questionnaire. Fish samples were analyzed for dichloro diphenyldichloro ethylene (DDE) and polychlorinated biphenyls (PCBs) content. Difference in difference model results showed that persistent organic pollutant (POP) exposure was positively associated with T2D in a dose-response manner. Stronger positive associations were found among females (OR = 14.96 (3.72–60.11)) than in males (OR = 2.85 (1.14–8.04)). The breakpoints for DDE and PCB intake were 2.11 ng/kg/day and 1.47 ng/kg/day, respectively. Each further 1 ng/kg/day increase in DDE and PCB intake increased the risk of T2D with ORs 2.29 (1.26–4.17) and 1.44 (1.09–1.89), respectively. Our findings suggest that the balance of risk and benefits associated with fish consumption is highly dependent on the regional POP concentrations in fish. Text First Nations PubMed Central (PMC) Canada International Journal of Environmental Research and Public Health 15 3 539 |
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Article Marushka, Lesya Hu, Xuefeng Batal, Malek Sadik, Tonio Schwartz, Harold Ing, Amy Fediuk, Karen Tikhonov, Constantine Chan, Hing Man The Relationship between Persistent Organic Pollutants Exposure and Type 2 Diabetes among First Nations in Ontario and Manitoba, Canada: A Difference in Difference Analysis |
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Article |
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We previously studied the association between fish consumption and prevalence of type 2 diabetes (T2D) in Manitoba and Ontario First Nations (FNs), Canada and found different results. In this study, we used a difference in difference model to analyze the data. Dietary and health data from the First Nations Food Nutrition and Environment Study, a cross-sectional study of 706 Manitoba and 1429 Ontario FNs were analyzed. The consumption of fish was estimated using a food frequency questionnaire. Fish samples were analyzed for dichloro diphenyldichloro ethylene (DDE) and polychlorinated biphenyls (PCBs) content. Difference in difference model results showed that persistent organic pollutant (POP) exposure was positively associated with T2D in a dose-response manner. Stronger positive associations were found among females (OR = 14.96 (3.72–60.11)) than in males (OR = 2.85 (1.14–8.04)). The breakpoints for DDE and PCB intake were 2.11 ng/kg/day and 1.47 ng/kg/day, respectively. Each further 1 ng/kg/day increase in DDE and PCB intake increased the risk of T2D with ORs 2.29 (1.26–4.17) and 1.44 (1.09–1.89), respectively. Our findings suggest that the balance of risk and benefits associated with fish consumption is highly dependent on the regional POP concentrations in fish. |
format |
Text |
author |
Marushka, Lesya Hu, Xuefeng Batal, Malek Sadik, Tonio Schwartz, Harold Ing, Amy Fediuk, Karen Tikhonov, Constantine Chan, Hing Man |
author_facet |
Marushka, Lesya Hu, Xuefeng Batal, Malek Sadik, Tonio Schwartz, Harold Ing, Amy Fediuk, Karen Tikhonov, Constantine Chan, Hing Man |
author_sort |
Marushka, Lesya |
title |
The Relationship between Persistent Organic Pollutants Exposure and Type 2 Diabetes among First Nations in Ontario and Manitoba, Canada: A Difference in Difference Analysis |
title_short |
The Relationship between Persistent Organic Pollutants Exposure and Type 2 Diabetes among First Nations in Ontario and Manitoba, Canada: A Difference in Difference Analysis |
title_full |
The Relationship between Persistent Organic Pollutants Exposure and Type 2 Diabetes among First Nations in Ontario and Manitoba, Canada: A Difference in Difference Analysis |
title_fullStr |
The Relationship between Persistent Organic Pollutants Exposure and Type 2 Diabetes among First Nations in Ontario and Manitoba, Canada: A Difference in Difference Analysis |
title_full_unstemmed |
The Relationship between Persistent Organic Pollutants Exposure and Type 2 Diabetes among First Nations in Ontario and Manitoba, Canada: A Difference in Difference Analysis |
title_sort |
relationship between persistent organic pollutants exposure and type 2 diabetes among first nations in ontario and manitoba, canada: a difference in difference analysis |
publisher |
MDPI |
publishDate |
2018 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877084/ http://www.ncbi.nlm.nih.gov/pubmed/29562596 https://doi.org/10.3390/ijerph15030539 |
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Canada |
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Canada |
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First Nations |
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First Nations |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877084/ http://www.ncbi.nlm.nih.gov/pubmed/29562596 http://dx.doi.org/10.3390/ijerph15030539 |
op_rights |
© 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
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CC-BY |
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https://doi.org/10.3390/ijerph15030539 |
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International Journal of Environmental Research and Public Health |
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15 |
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3 |
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539 |
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1766001074927304704 |