Basal cell adenocarcinoma in the gland of the third eyelid of a brown bear (Ursus arctos)
The right third eyelid of an adult female brown bear (c) was swollen and removed. Histopathology revealed a tumor exhibiting proliferation with mild infiltration, consisting of multi-stratified glandular structures of the innermost laminal neoplastic cells and the basaloid neoplastic cells, and with...
| Published in: | Journal of Veterinary Medical Science |
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| Main Authors: | , , |
| Format: | Text |
| Language: | English |
| Published: |
The Japanese Society of Veterinary Science
2017
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| Subjects: | |
| Online Access: | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573820/ http://www.ncbi.nlm.nih.gov/pubmed/28637946 https://doi.org/10.1292/jvms.17-0264 |
| Summary: | The right third eyelid of an adult female brown bear (c) was swollen and removed. Histopathology revealed a tumor exhibiting proliferation with mild infiltration, consisting of multi-stratified glandular structures of the innermost laminal neoplastic cells and the basaloid neoplastic cells, and with eosinophilic thick basal lamina material around the glandular structures. Both types of neoplastic cells exhibited moderate anisokaryosis, and mitotic figures were observed in the basaloid neoplastic cells. The laminal neoplastic cells were cytokeratin (CK) 8/18-positive. In contrast, the basaloid neoplastic cells were CK14- and p63-positive, but α-smooth muscle actin- and calponin-negative. The case described herein is the first report of basal cell adenocarcinoma in the gland of the third eyelid of a bear. |
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