Hepatitis B among Inuit: A review with focus on Greenland Inuit
Hepatitis B virus (HBV) infection is a disease with a highly variable course. Chronic HBV infection may cause end-stage liver disease including cirrhosis and hepatocellular carcinoma, which is the 3rd most common cause of cancer related death due to the poor prognosis. The prevalence of HBV infectio...
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ftpubmed:oai:pubmedcentral.nih.gov:4438501 2023-05-15T14:50:49+02:00 Hepatitis B among Inuit: A review with focus on Greenland Inuit Rex, Karsten Fleischer Andersen, Stig Krarup, Henrik Bygum 2015-05-28 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438501/ http://www.ncbi.nlm.nih.gov/pubmed/26019742 https://doi.org/10.4254/wjh.v7.i9.1265 en eng Baishideng Publishing Group Inc http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438501/ http://www.ncbi.nlm.nih.gov/pubmed/26019742 http://dx.doi.org/10.4254/wjh.v7.i9.1265 ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved. Minireviews Text 2015 ftpubmed https://doi.org/10.4254/wjh.v7.i9.1265 2015-05-31T00:03:48Z Hepatitis B virus (HBV) infection is a disease with a highly variable course. Chronic HBV infection may cause end-stage liver disease including cirrhosis and hepatocellular carcinoma, which is the 3rd most common cause of cancer related death due to the poor prognosis. The prevalence of HBV infection is low in many countries. Still, it remains important due to the potential consequences of the disease. HBV is endemic in the Arctic with serologic markers of chronic HBV infection in up to 29% of the population in some areas in Greenland. Interestingly, Inuit populations rarely show signs of liver disease despite the fact that around half of all Inuit has been exposed to HBV and around 8% of Inuit are chronically infected with HBV. These findings have been consistent in surveys conducted for more than four decades among Arctic Inuit. We thus review HBV infection in the Arctic with focus on Greenland Inuit and compared with Inuit in Canada, Alaska and Siberia. The aspects described include epidemiology and monitoring of the disease, as well as treatment and the risk of liver cancer. Text Arctic Greenland inuit Alaska Siberia PubMed Central (PMC) Arctic Canada Greenland World Journal of Hepatology 7 9 1265 |
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Minireviews Rex, Karsten Fleischer Andersen, Stig Krarup, Henrik Bygum Hepatitis B among Inuit: A review with focus on Greenland Inuit |
topic_facet |
Minireviews |
description |
Hepatitis B virus (HBV) infection is a disease with a highly variable course. Chronic HBV infection may cause end-stage liver disease including cirrhosis and hepatocellular carcinoma, which is the 3rd most common cause of cancer related death due to the poor prognosis. The prevalence of HBV infection is low in many countries. Still, it remains important due to the potential consequences of the disease. HBV is endemic in the Arctic with serologic markers of chronic HBV infection in up to 29% of the population in some areas in Greenland. Interestingly, Inuit populations rarely show signs of liver disease despite the fact that around half of all Inuit has been exposed to HBV and around 8% of Inuit are chronically infected with HBV. These findings have been consistent in surveys conducted for more than four decades among Arctic Inuit. We thus review HBV infection in the Arctic with focus on Greenland Inuit and compared with Inuit in Canada, Alaska and Siberia. The aspects described include epidemiology and monitoring of the disease, as well as treatment and the risk of liver cancer. |
format |
Text |
author |
Rex, Karsten Fleischer Andersen, Stig Krarup, Henrik Bygum |
author_facet |
Rex, Karsten Fleischer Andersen, Stig Krarup, Henrik Bygum |
author_sort |
Rex, Karsten Fleischer |
title |
Hepatitis B among Inuit: A review with focus on Greenland Inuit |
title_short |
Hepatitis B among Inuit: A review with focus on Greenland Inuit |
title_full |
Hepatitis B among Inuit: A review with focus on Greenland Inuit |
title_fullStr |
Hepatitis B among Inuit: A review with focus on Greenland Inuit |
title_full_unstemmed |
Hepatitis B among Inuit: A review with focus on Greenland Inuit |
title_sort |
hepatitis b among inuit: a review with focus on greenland inuit |
publisher |
Baishideng Publishing Group Inc |
publishDate |
2015 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438501/ http://www.ncbi.nlm.nih.gov/pubmed/26019742 https://doi.org/10.4254/wjh.v7.i9.1265 |
geographic |
Arctic Canada Greenland |
geographic_facet |
Arctic Canada Greenland |
genre |
Arctic Greenland inuit Alaska Siberia |
genre_facet |
Arctic Greenland inuit Alaska Siberia |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438501/ http://www.ncbi.nlm.nih.gov/pubmed/26019742 http://dx.doi.org/10.4254/wjh.v7.i9.1265 |
op_rights |
©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved. |
op_doi |
https://doi.org/10.4254/wjh.v7.i9.1265 |
container_title |
World Journal of Hepatology |
container_volume |
7 |
container_issue |
9 |
container_start_page |
1265 |
_version_ |
1766321861913739264 |