Notes on the Epidemiology of Multiple Sclerosis, with Special Reference to Dietary Habits

A hypothesis, based primarily on the occurrence of multiple sclerosis (MS) in the Faroe Islands and supported by numerous analytical epidemiological studies, is described. It proposes that MS is caused by the interaction of a virus disease with intestinal pathology, e.g., infectious mononucleosis, a...

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Published in:International Journal of Molecular Sciences
Main Author: Lauer, Klaus
Format: Text
Language:English
Published: Molecular Diversity Preservation International (MDPI) 2014
Subjects:
Review
Faroe Islands
Online Access:http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975352
http://www.ncbi.nlm.nih.gov/pubmed/24577315
https://doi.org/10.3390/ijms15033533
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spelling ftpubmed:oai:pubmedcentral.nih.gov:3975352 2023-05-15T16:10:40+02:00 Notes on the Epidemiology of Multiple Sclerosis, with Special Reference to Dietary Habits Lauer, Klaus 2014-02-26 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975352 http://www.ncbi.nlm.nih.gov/pubmed/24577315 https://doi.org/10.3390/ijms15033533 en eng Molecular Diversity Preservation International (MDPI) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975352 http://www.ncbi.nlm.nih.gov/pubmed/24577315 http://dx.doi.org/10.3390/ijms15033533 © 2014 by the authors; licensee MDPI, Basel, Switzerland http://creativecommons.org/licenses/by/3.0/ This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/). CC-BY Review Text 2014 ftpubmed https://doi.org/10.3390/ijms15033533 2014-04-06T01:27:57Z A hypothesis, based primarily on the occurrence of multiple sclerosis (MS) in the Faroe Islands and supported by numerous analytical epidemiological studies, is described. It proposes that MS is caused by the interaction of a virus disease with intestinal pathology, e.g., infectious mononucleosis, and application of smoked and nitrate/nitrite-cured meat products in the diet during circumscribed time intervals. The biological mechanisms might involve a break of tolerance by an alteration of self within the central nervous system, by nitrophenylated compounds conjugated to animal tissue, in particular to proteins occurring in the central nervous system. Further research is needed. Text Faroe Islands PubMed Central (PMC) Faroe Islands International Journal of Molecular Sciences 15 3 3533 3545
institution Open Polar
collection PubMed Central (PMC)
op_collection_id ftpubmed
language English
topic Review
spellingShingle Review
Lauer, Klaus
Notes on the Epidemiology of Multiple Sclerosis, with Special Reference to Dietary Habits
topic_facet Review
description A hypothesis, based primarily on the occurrence of multiple sclerosis (MS) in the Faroe Islands and supported by numerous analytical epidemiological studies, is described. It proposes that MS is caused by the interaction of a virus disease with intestinal pathology, e.g., infectious mononucleosis, and application of smoked and nitrate/nitrite-cured meat products in the diet during circumscribed time intervals. The biological mechanisms might involve a break of tolerance by an alteration of self within the central nervous system, by nitrophenylated compounds conjugated to animal tissue, in particular to proteins occurring in the central nervous system. Further research is needed.
format Text
author Lauer, Klaus
author_facet Lauer, Klaus
author_sort Lauer, Klaus
title Notes on the Epidemiology of Multiple Sclerosis, with Special Reference to Dietary Habits
title_short Notes on the Epidemiology of Multiple Sclerosis, with Special Reference to Dietary Habits
title_full Notes on the Epidemiology of Multiple Sclerosis, with Special Reference to Dietary Habits
title_fullStr Notes on the Epidemiology of Multiple Sclerosis, with Special Reference to Dietary Habits
title_full_unstemmed Notes on the Epidemiology of Multiple Sclerosis, with Special Reference to Dietary Habits
title_sort notes on the epidemiology of multiple sclerosis, with special reference to dietary habits
publisher Molecular Diversity Preservation International (MDPI)
publishDate 2014
url http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975352
http://www.ncbi.nlm.nih.gov/pubmed/24577315
https://doi.org/10.3390/ijms15033533
geographic Faroe Islands
geographic_facet Faroe Islands
genre Faroe Islands
genre_facet Faroe Islands
op_relation http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975352
http://www.ncbi.nlm.nih.gov/pubmed/24577315
http://dx.doi.org/10.3390/ijms15033533
op_rights © 2014 by the authors; licensee MDPI, Basel, Switzerland
http://creativecommons.org/licenses/by/3.0/
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
op_rightsnorm CC-BY
op_doi https://doi.org/10.3390/ijms15033533
container_title International Journal of Molecular Sciences
container_volume 15
container_issue 3
container_start_page 3533
op_container_end_page 3545
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