Notes on the Epidemiology of Multiple Sclerosis, with Special Reference to Dietary Habits

A hypothesis, based primarily on the occurrence of multiple sclerosis (MS) in the Faroe Islands and supported by numerous analytical epidemiological studies, is described. It proposes that MS is caused by the interaction of a virus disease with intestinal pathology, e.g., infectious mononucleosis, a...

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Bibliographic Details
Published in:International Journal of Molecular Sciences
Main Author: Lauer, Klaus
Format: Text
Language:English
Published: Molecular Diversity Preservation International (MDPI) 2014
Subjects:
Online Access:http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975352
http://www.ncbi.nlm.nih.gov/pubmed/24577315
https://doi.org/10.3390/ijms15033533
Description
Summary:A hypothesis, based primarily on the occurrence of multiple sclerosis (MS) in the Faroe Islands and supported by numerous analytical epidemiological studies, is described. It proposes that MS is caused by the interaction of a virus disease with intestinal pathology, e.g., infectious mononucleosis, and application of smoked and nitrate/nitrite-cured meat products in the diet during circumscribed time intervals. The biological mechanisms might involve a break of tolerance by an alteration of self within the central nervous system, by nitrophenylated compounds conjugated to animal tissue, in particular to proteins occurring in the central nervous system. Further research is needed.