Coronary artery calcium distributions in older persons in the AGES-Reykjavik study
Coronary Artery Calcium (CAC) is a sign of advanced atherosclerosis and an independent risk factor for cardiac events. Here, we describe CAC-distributions in an unselected aged population and compare modelling methods to characterize CAC-distribution. CAC is difficult to model because it has a skewe...
Published in: | European Journal of Epidemiology |
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Main Authors: | , , , , , |
Format: | Text |
Language: | English |
Published: |
2012
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Subjects: | |
Online Access: | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3746182 http://www.ncbi.nlm.nih.gov/pubmed/22990371 https://doi.org/10.1007/s10654-012-9730-6 |
Summary: | Coronary Artery Calcium (CAC) is a sign of advanced atherosclerosis and an independent risk factor for cardiac events. Here, we describe CAC-distributions in an unselected aged population and compare modelling methods to characterize CAC-distribution. CAC is difficult to model because it has a skewed and zero inflated distribution with over-dispersion. Data are from the AGES-Reykjavik sample, a large population based study [2002-2006] in Iceland of 5,764 persons aged 66-96 years. |
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