Crystal structure of a putative isochorismatase hydrolase from Oleispira antarctica

Isochorismatase-like hydrolases (IHL) constitute a large family of enzymes divided into five structural families (by SCOP). IHLs are crucial for siderophore-mediated ferric iron acquisition by cells. Knowledge of the structural characteristics of these molecules will enhance the understanding of the...

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Bibliographic Details
Published in:Journal of Structural and Functional Genomics
Main Authors: Goral, Anna M., Tkaczuk, Karolina L., Chruszcz, Maksymilian, Kagan, Olga, Savchenko, Alexei, Minor, Wladek
Format: Text
Language:English
Published: 2012
Subjects:
Article
Ihl
Antarc*
Antarctica
Online Access:http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328404
http://www.ncbi.nlm.nih.gov/pubmed/22350524
https://doi.org/10.1007/s10969-012-9127-5
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Summary:Isochorismatase-like hydrolases (IHL) constitute a large family of enzymes divided into five structural families (by SCOP). IHLs are crucial for siderophore-mediated ferric iron acquisition by cells. Knowledge of the structural characteristics of these molecules will enhance the understanding of the molecular basis of iron transport, and perhaps resolve which of the mechanisms previously proposed in the literature is the correct one.

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