Chemoenzymatic Synthesis of 2-Arachidonoylglycerol, An Endogenous Ligand for Cannabinoid Receptors

A simple and efficient synthesis of 2-arachidonoyl glycerol, an endogenous agonist for cannabinoid receptors was achieved using Novozym 435, immobilized lipase from Candida Antarctica.

Bibliographic Details
Published in:Tetrahedron Letters
Main Authors: Vadivel, Subramanian K, Whitten, Kyle M, Makriyannis, A.
Format: Text
Language:English
Published: 2011
Subjects:
Article
Antarc*
Antarctica
Online Access:http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035909
http://www.ncbi.nlm.nih.gov/pubmed/21318079
https://doi.org/10.1016/j.tetlet.2011.01.047
Description
Summary:A simple and efficient synthesis of 2-arachidonoyl glycerol, an endogenous agonist for cannabinoid receptors was achieved using Novozym 435, immobilized lipase from Candida Antarctica.

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