Mannose-Binding Lectin Genotypes and Susceptibility to Epstein-Barr Virus Infection in Infancy▿

In a cohort study of children <4 years of age in Greenland, mannose-binding lectin (MBL2) genotypes and Epstein-Barr virus (EBV) antibody levels were determined. EBV seropositivity was significantly lower and time to seroconversion increased in MBL-insufficient compared with MBL-sufficient childr...

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Published in:Clinical and Vaccine Immunology
Main Authors: Friborg, Jeppe T., Jarrett, Ruth F., Koch, Anders, Garred, Peter, Freeland, June M. L., Andersen, Andreas, Melbye, Mads
Format: Text
Language:English
Published: American Society for Microbiology (ASM) 2010
Subjects:
Microbial Immunology
Greenland
Online Access:http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2944456
http://www.ncbi.nlm.nih.gov/pubmed/20610664
https://doi.org/10.1128/CVI.00527-09
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spelling ftpubmed:oai:pubmedcentral.nih.gov:2944456 2023-05-15T16:27:24+02:00 Mannose-Binding Lectin Genotypes and Susceptibility to Epstein-Barr Virus Infection in Infancy▿ Friborg, Jeppe T. Jarrett, Ruth F. Koch, Anders Garred, Peter Freeland, June M. L. Andersen, Andreas Melbye, Mads 2010-09 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2944456 http://www.ncbi.nlm.nih.gov/pubmed/20610664 https://doi.org/10.1128/CVI.00527-09 en eng American Society for Microbiology (ASM) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2944456 http://www.ncbi.nlm.nih.gov/pubmed/20610664 http://dx.doi.org/10.1128/CVI.00527-09 Copyright © 2010, American Society for Microbiology Microbial Immunology Text 2010 ftpubmed https://doi.org/10.1128/CVI.00527-09 2013-09-03T05:06:10Z In a cohort study of children <4 years of age in Greenland, mannose-binding lectin (MBL2) genotypes and Epstein-Barr virus (EBV) antibody levels were determined. EBV seropositivity was significantly lower and time to seroconversion increased in MBL-insufficient compared with MBL-sufficient children, indicating that MBL may be involved in primary EBV infection in infancy. Text Greenland PubMed Central (PMC) Greenland Clinical and Vaccine Immunology 17 9 1484 1487
institution Open Polar
collection PubMed Central (PMC)
op_collection_id ftpubmed
language English
topic Microbial Immunology
spellingShingle Microbial Immunology
Friborg, Jeppe T.
Jarrett, Ruth F.
Koch, Anders
Garred, Peter
Freeland, June M. L.
Andersen, Andreas
Melbye, Mads
Mannose-Binding Lectin Genotypes and Susceptibility to Epstein-Barr Virus Infection in Infancy▿
topic_facet Microbial Immunology
description In a cohort study of children <4 years of age in Greenland, mannose-binding lectin (MBL2) genotypes and Epstein-Barr virus (EBV) antibody levels were determined. EBV seropositivity was significantly lower and time to seroconversion increased in MBL-insufficient compared with MBL-sufficient children, indicating that MBL may be involved in primary EBV infection in infancy.
format Text
author Friborg, Jeppe T.
Jarrett, Ruth F.
Koch, Anders
Garred, Peter
Freeland, June M. L.
Andersen, Andreas
Melbye, Mads
author_facet Friborg, Jeppe T.
Jarrett, Ruth F.
Koch, Anders
Garred, Peter
Freeland, June M. L.
Andersen, Andreas
Melbye, Mads
author_sort Friborg, Jeppe T.
title Mannose-Binding Lectin Genotypes and Susceptibility to Epstein-Barr Virus Infection in Infancy▿
title_short Mannose-Binding Lectin Genotypes and Susceptibility to Epstein-Barr Virus Infection in Infancy▿
title_full Mannose-Binding Lectin Genotypes and Susceptibility to Epstein-Barr Virus Infection in Infancy▿
title_fullStr Mannose-Binding Lectin Genotypes and Susceptibility to Epstein-Barr Virus Infection in Infancy▿
title_full_unstemmed Mannose-Binding Lectin Genotypes and Susceptibility to Epstein-Barr Virus Infection in Infancy▿
title_sort mannose-binding lectin genotypes and susceptibility to epstein-barr virus infection in infancy▿
publisher American Society for Microbiology (ASM)
publishDate 2010
url http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2944456
http://www.ncbi.nlm.nih.gov/pubmed/20610664
https://doi.org/10.1128/CVI.00527-09
geographic Greenland
geographic_facet Greenland
genre Greenland
genre_facet Greenland
op_relation http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2944456
http://www.ncbi.nlm.nih.gov/pubmed/20610664
http://dx.doi.org/10.1128/CVI.00527-09
op_rights Copyright © 2010, American Society for Microbiology
op_doi https://doi.org/10.1128/CVI.00527-09
container_title Clinical and Vaccine Immunology
container_volume 17
container_issue 9
container_start_page 1484
op_container_end_page 1487
_version_ 1766016572355248128

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