Synthesis of 3-Alkyl Pyridinium Alkaloids from the Arctic Sponge Haliclona viscosa

3-Alkyl pyridinium alkaloids (3-APAs) are common secondary metabolites in marine sponges of the order Haplosclerida. In recent years, our laboratory has isolated and synthesized several new members of this family such as haliclamines C–F, viscosamine, viscosaline and a cyclic monomer. All of them we...

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Published in:Marine Drugs
Main Authors: Timm, Christoph, Mordhorst, Thorsten, Köck, Matthias
Format: Text
Language:English
Published: Molecular Diversity Preservation International 2010
Subjects:
Review
Arctic
Norway
Spitsbergen
Online Access:http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857371
http://www.ncbi.nlm.nih.gov/pubmed/20411111
https://doi.org/10.3390/md8030483
id ftpubmed:oai:pubmedcentral.nih.gov:2857371
record_format openpolar
spelling ftpubmed:oai:pubmedcentral.nih.gov:2857371 2023-05-15T14:48:59+02:00 Synthesis of 3-Alkyl Pyridinium Alkaloids from the Arctic Sponge Haliclona viscosa Timm, Christoph Mordhorst, Thorsten Köck, Matthias 2010-03-05 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857371 http://www.ncbi.nlm.nih.gov/pubmed/20411111 https://doi.org/10.3390/md8030483 en eng Molecular Diversity Preservation International http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857371 http://www.ncbi.nlm.nih.gov/pubmed/20411111 http://dx.doi.org/10.3390/md8030483 © 2010 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland http://creativecommons.org/licenses/by/3.0 This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/). CC-BY Review Text 2010 ftpubmed https://doi.org/10.3390/md8030483 2013-09-02T23:39:59Z 3-Alkyl pyridinium alkaloids (3-APAs) are common secondary metabolites in marine sponges of the order Haplosclerida. In recent years, our laboratory has isolated and synthesized several new members of this family such as haliclamines C–F, viscosamine, viscosaline and a cyclic monomer. All of them were isolated from the Arctic sponge Haliclona viscosa collected in Spitsbergen, Norway. In this article we report the syntheses of these secondary metabolites from Haliclona viscosa and related compounds and give a short overview of the bioactivity. Text Arctic Spitsbergen PubMed Central (PMC) Arctic Norway Marine Drugs 8 3 483 497
institution Open Polar
collection PubMed Central (PMC)
op_collection_id ftpubmed
language English
topic Review
spellingShingle Review
Timm, Christoph
Mordhorst, Thorsten
Köck, Matthias
Synthesis of 3-Alkyl Pyridinium Alkaloids from the Arctic Sponge Haliclona viscosa
topic_facet Review
description 3-Alkyl pyridinium alkaloids (3-APAs) are common secondary metabolites in marine sponges of the order Haplosclerida. In recent years, our laboratory has isolated and synthesized several new members of this family such as haliclamines C–F, viscosamine, viscosaline and a cyclic monomer. All of them were isolated from the Arctic sponge Haliclona viscosa collected in Spitsbergen, Norway. In this article we report the syntheses of these secondary metabolites from Haliclona viscosa and related compounds and give a short overview of the bioactivity.
format Text
author Timm, Christoph
Mordhorst, Thorsten
Köck, Matthias
author_facet Timm, Christoph
Mordhorst, Thorsten
Köck, Matthias
author_sort Timm, Christoph
title Synthesis of 3-Alkyl Pyridinium Alkaloids from the Arctic Sponge Haliclona viscosa
title_short Synthesis of 3-Alkyl Pyridinium Alkaloids from the Arctic Sponge Haliclona viscosa
title_full Synthesis of 3-Alkyl Pyridinium Alkaloids from the Arctic Sponge Haliclona viscosa
title_fullStr Synthesis of 3-Alkyl Pyridinium Alkaloids from the Arctic Sponge Haliclona viscosa
title_full_unstemmed Synthesis of 3-Alkyl Pyridinium Alkaloids from the Arctic Sponge Haliclona viscosa
title_sort synthesis of 3-alkyl pyridinium alkaloids from the arctic sponge haliclona viscosa
publisher Molecular Diversity Preservation International
publishDate 2010
url http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857371
http://www.ncbi.nlm.nih.gov/pubmed/20411111
https://doi.org/10.3390/md8030483
geographic Arctic
Norway
geographic_facet Arctic
Norway
genre Arctic
Spitsbergen
genre_facet Arctic
Spitsbergen
op_relation http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857371
http://www.ncbi.nlm.nih.gov/pubmed/20411111
http://dx.doi.org/10.3390/md8030483
op_rights © 2010 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland
http://creativecommons.org/licenses/by/3.0
This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
op_rightsnorm CC-BY
op_doi https://doi.org/10.3390/md8030483
container_title Marine Drugs
container_volume 8
container_issue 3
container_start_page 483
op_container_end_page 497
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