N-acylation of ethanolamine using lipase: a chemoselective catalyst
The N-acylation of ethanolamine (2) with various fatty acids 1a–d and esters of fatty acids 1e–h using Candida antarctica B lipase (Novozym® 435) are described and optimum conditions for selective N-acylation rather than O-acylation are also discussed. Microwave assisted solution phase, solid suppor...
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ftpubmed:oai:pubmedcentral.nih.gov:2686314 2023-05-15T13:39:48+02:00 N-acylation of ethanolamine using lipase: a chemoselective catalyst Kidwai, Mazaahir Poddar, Roona Mothsra, Poonam 2009-03-25 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2686314 http://www.ncbi.nlm.nih.gov/pubmed/19478911 https://doi.org/10.3762/bjoc.5.10 en eng Beilstein-Institut http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2686314 http://www.ncbi.nlm.nih.gov/pubmed/19478911 http://dx.doi.org/10.3762/bjoc.5.10 Copyright © 2009, Kidwai et al; licensee Beilstein-Institut. http://www.beilstein-journals.org/bjoc This is an Open Access article under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (http://www.beilstein-journals.org/bjoc) CC-BY Preliminary Communication Text 2009 ftpubmed https://doi.org/10.3762/bjoc.5.10 2013-09-02T13:18:30Z The N-acylation of ethanolamine (2) with various fatty acids 1a–d and esters of fatty acids 1e–h using Candida antarctica B lipase (Novozym® 435) are described and optimum conditions for selective N-acylation rather than O-acylation are also discussed. Microwave assisted solution phase, solid supported and conventional methods were investigated and results were compared. There is a synergy between the enzyme catalysis and microwave irradiation. Text Antarc* Antarctica PubMed Central (PMC) Beilstein Journal of Organic Chemistry 5 |
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PubMed Central (PMC) |
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ftpubmed |
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English |
topic |
Preliminary Communication |
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Preliminary Communication Kidwai, Mazaahir Poddar, Roona Mothsra, Poonam N-acylation of ethanolamine using lipase: a chemoselective catalyst |
topic_facet |
Preliminary Communication |
description |
The N-acylation of ethanolamine (2) with various fatty acids 1a–d and esters of fatty acids 1e–h using Candida antarctica B lipase (Novozym® 435) are described and optimum conditions for selective N-acylation rather than O-acylation are also discussed. Microwave assisted solution phase, solid supported and conventional methods were investigated and results were compared. There is a synergy between the enzyme catalysis and microwave irradiation. |
format |
Text |
author |
Kidwai, Mazaahir Poddar, Roona Mothsra, Poonam |
author_facet |
Kidwai, Mazaahir Poddar, Roona Mothsra, Poonam |
author_sort |
Kidwai, Mazaahir |
title |
N-acylation of ethanolamine using lipase: a chemoselective catalyst |
title_short |
N-acylation of ethanolamine using lipase: a chemoselective catalyst |
title_full |
N-acylation of ethanolamine using lipase: a chemoselective catalyst |
title_fullStr |
N-acylation of ethanolamine using lipase: a chemoselective catalyst |
title_full_unstemmed |
N-acylation of ethanolamine using lipase: a chemoselective catalyst |
title_sort |
n-acylation of ethanolamine using lipase: a chemoselective catalyst |
publisher |
Beilstein-Institut |
publishDate |
2009 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2686314 http://www.ncbi.nlm.nih.gov/pubmed/19478911 https://doi.org/10.3762/bjoc.5.10 |
genre |
Antarc* Antarctica |
genre_facet |
Antarc* Antarctica |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2686314 http://www.ncbi.nlm.nih.gov/pubmed/19478911 http://dx.doi.org/10.3762/bjoc.5.10 |
op_rights |
Copyright © 2009, Kidwai et al; licensee Beilstein-Institut. http://www.beilstein-journals.org/bjoc This is an Open Access article under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (http://www.beilstein-journals.org/bjoc) |
op_rightsnorm |
CC-BY |
op_doi |
https://doi.org/10.3762/bjoc.5.10 |
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Beilstein Journal of Organic Chemistry |
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5 |
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1766125099330568192 |