Simultaneous measurement of brain tissue oxygen partial pressure, temperature, and global oxygen consumption during hibernation, arousal, and euthermy in non-sedated and non-anesthetized Arctic ground squirrels

This study reports an online temperature correction method for determining tissue oxygen partial pressure (PtO2) in the striatum and a novel simultaneous measurement of brain PtO2 and temperature (Tbrain) in conjunction with global oxygen consumption (VO2) in non-sedated and non-anesthetized freely...

Full description

Bibliographic Details
Published in:Journal of Neuroscience Methods
Main Authors: Ma, Yilong, Wu, Shufen
Format: Text
Language:English
Published: 2008
Subjects:
Article
Arctic
Online Access:http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615241
http://www.ncbi.nlm.nih.gov/pubmed/18722471
https://doi.org/10.1016/j.jneumeth.2008.07.011
Description
Summary:This study reports an online temperature correction method for determining tissue oxygen partial pressure (PtO2) in the striatum and a novel simultaneous measurement of brain PtO2 and temperature (Tbrain) in conjunction with global oxygen consumption (VO2) in non-sedated and non-anesthetized freely moving Arctic ground squirrels (AGS, Spermophilus parryii). This method fills an important research gap—the lack of a suitable method for physiologic studies of tissue PO2 in hibernating or other cool-blooded species.

Similar Items