A subset of memory CD4+ helper T lymphocytes identified by expression of Pgp-1

The Pgp-1 glycoprotein (Ly-24 antigen) is acquired by mature murine T lymphocytes at the time of primary antigen stimulation Pgp-1 was previously shown to be a useful cell surface marker for distinguishing antigen-specific memory CD8+ T lymphocytes after immunization. Here we demonstrate that this o...

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Format: Text
Language:English
Published: The Rockefeller University Press 1989
Subjects:
Online Access:http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2189224
http://www.ncbi.nlm.nih.gov/pubmed/2564418
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spelling ftpubmed:oai:pubmedcentral.nih.gov:2189224 2023-05-15T18:26:39+02:00 A subset of memory CD4+ helper T lymphocytes identified by expression of Pgp-1 1989-04-01 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2189224 http://www.ncbi.nlm.nih.gov/pubmed/2564418 en eng The Rockefeller University Press http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2189224 http://www.ncbi.nlm.nih.gov/pubmed/2564418 Articles Text 1989 ftpubmed 2013-09-01T12:38:55Z The Pgp-1 glycoprotein (Ly-24 antigen) is acquired by mature murine T lymphocytes at the time of primary antigen stimulation Pgp-1 was previously shown to be a useful cell surface marker for distinguishing antigen-specific memory CD8+ T lymphocytes after immunization. Here we demonstrate that this observation extends to CD4+ T lymphocytes. Antigen-specific CD4+ T cells in mice immunized with sperm whale myoglobin or keyhole limpet hemocyanin were contained nearly exclusively in the minor Pgp-1+ subset. Text Sperm whale PubMed Central (PMC) Keyhole ENVELOPE(-67.338,-67.338,-68.785,-68.785)
institution Open Polar
collection PubMed Central (PMC)
op_collection_id ftpubmed
language English
topic Articles
spellingShingle Articles
A subset of memory CD4+ helper T lymphocytes identified by expression of Pgp-1
topic_facet Articles
description The Pgp-1 glycoprotein (Ly-24 antigen) is acquired by mature murine T lymphocytes at the time of primary antigen stimulation Pgp-1 was previously shown to be a useful cell surface marker for distinguishing antigen-specific memory CD8+ T lymphocytes after immunization. Here we demonstrate that this observation extends to CD4+ T lymphocytes. Antigen-specific CD4+ T cells in mice immunized with sperm whale myoglobin or keyhole limpet hemocyanin were contained nearly exclusively in the minor Pgp-1+ subset.
format Text
title A subset of memory CD4+ helper T lymphocytes identified by expression of Pgp-1
title_short A subset of memory CD4+ helper T lymphocytes identified by expression of Pgp-1
title_full A subset of memory CD4+ helper T lymphocytes identified by expression of Pgp-1
title_fullStr A subset of memory CD4+ helper T lymphocytes identified by expression of Pgp-1
title_full_unstemmed A subset of memory CD4+ helper T lymphocytes identified by expression of Pgp-1
title_sort subset of memory cd4+ helper t lymphocytes identified by expression of pgp-1
publisher The Rockefeller University Press
publishDate 1989
url http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2189224
http://www.ncbi.nlm.nih.gov/pubmed/2564418
long_lat ENVELOPE(-67.338,-67.338,-68.785,-68.785)
geographic Keyhole
geographic_facet Keyhole
genre Sperm whale
genre_facet Sperm whale
op_relation http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2189224
http://www.ncbi.nlm.nih.gov/pubmed/2564418
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