gyrA and parC Mutations and Associated Quinolone Resistance in Vibrio anguillarum Serotype O2b Strains Isolated from Farmed Atlantic Cod (Gadus morhua) in Norway▿

MIC testing of Vibrio anguillarum isolates recovered from diseased farmed Atlantic cod revealed oxolinic acid MICs of ≤0.001, 0.06, and 16 μg ml−1. Single gyrA Ser-Ile substitutions were identified at position 83 of the intermediate and resistant strains, while a parC Ser-Leu substitution at positio...

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Bibliographic Details
Published in:Antimicrobial Agents and Chemotherapy
Main Authors: Colquhoun, D. J., Aarflot, L., Melvold, C. F.
Format: Text
Language:English
Published: American Society for Microbiology (ASM) 2007
Subjects:
Mechanisms of Resistance
Norway
atlantic cod
Gadus morhua
Online Access:http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1913251
http://www.ncbi.nlm.nih.gov/pubmed/17502408
https://doi.org/10.1128/AAC.00315-07
Description
Summary:MIC testing of Vibrio anguillarum isolates recovered from diseased farmed Atlantic cod revealed oxolinic acid MICs of ≤0.001, 0.06, and 16 μg ml−1. Single gyrA Ser-Ile substitutions were identified at position 83 of the intermediate and resistant strains, while a parC Ser-Leu substitution at position 85 was found only in the resistant strain.

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