Cross-Reactive Neuraminidase Antibodies Afford Partial Protection against H5N1 in Mice and Are Present in Unexposed Humans

Humoral immunity against endemic human H1N1 influenza viruses can partially protect mice against H5N1 challenge, raising the possibility that a portion of the human population could have some degree of resistance against avian flu.

Bibliographic Details
Published in:PLoS Medicine
Main Authors: Sandbulte, Matthew R, Jimenez, Gretchen S, Boon, Adrianus C. M, Smith, Larry R, Treanor, John J, Webby, Richard J
Format: Text
Language:English
Published: Public Library of Science 2007
Subjects:
Research Article
Avian flu
Online Access:http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1796909
http://www.ncbi.nlm.nih.gov/pubmed/17298168
https://doi.org/10.1371/journal.pmed.0040059
Description
Summary:Humoral immunity against endemic human H1N1 influenza viruses can partially protect mice against H5N1 challenge, raising the possibility that a portion of the human population could have some degree of resistance against avian flu.

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