Family studies of relation between Perthes disease and congenital dislocation of the hip

A family study of Perthes disease and congenital dislocation of the hip was made in the Faroe Islands, with a population of 40 000. The examination included 1123 sibs and first cousins of 43 probands with Perthes disease, 1942 sibs and first cousins of 59 dislocation probands, and 5205 sibs and firs...

Full description

Bibliographic Details
Main Author: Niclasen, Sanna Dahl
Format: Text
Language:English
Published: 1978
Subjects:
Online Access:http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1013702
http://www.ncbi.nlm.nih.gov/pubmed/712763
Description
Summary:A family study of Perthes disease and congenital dislocation of the hip was made in the Faroe Islands, with a population of 40 000. The examination included 1123 sibs and first cousins of 43 probands with Perthes disease, 1942 sibs and first cousins of 59 dislocation probands, and 5205 sibs and first cousins of 172 unaffected matched controls. Both conditions occur with exceptionally high incidences in this population. Thus the incidence of Perthes disease was found to be 41: 10 000 males and 7: 10 000 females, of congenital dislocation of the hip 7: 10 000 males and 59: 10 000 females. These figures are 3 to 4 times higher than those commonly observed in Caucasian populations.