The Use of Intact Fish Skin as a Novel Treatment Method for Deep Dermal Burns Following Enzymatic Debridement: A Retrospective Case-Control Study.

The optimal therapy for deep burn wounds is based on the early debridement of necrotic tissue followed by wound coverage to avoid a systemic inflammatory response and optimize scar-free healing. The outcomes are affected by available resources and underlying patient factors, which represent challeng...

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Bibliographic Details
Published in:European Burn Journal
Main Authors: Wallner, Christoph, Holtermann, Jana, Drysch, Marius, Schmidt, Sonja, Reinkemeier, Felix, Wagner, Johannes Maximilian, Dadras, Mehran, Sogorski, Alexander, Houschyar, Khosrow Siamak, Becerikli, Mustafa, Lehnhardt, Marcus, Behr, Björn
Format: Article in Journal/Newspaper
Language:English
Published: MDPI 2022
Subjects:
acellular fish skin graft
scarring
severe burn injuries
wound healing
wound matrix
xenotransplantation
Iceland
Online Access:https://doi.org/10.3390/ebj3010006
https://pubmed.ncbi.nlm.nih.gov/39604176
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11575382/
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Summary:The optimal therapy for deep burn wounds is based on the early debridement of necrotic tissue followed by wound coverage to avoid a systemic inflammatory response and optimize scar-free healing. The outcomes are affected by available resources and underlying patient factors, which represent challenges in burn care and suboptimal outcomes. In this study, we aimed to determine optimal burn-wound management using enzymatic debridement (NexoBrid™, MediWound Germany GmbH, Rüsselsheim, Germany) and intact fish skin (Kerecis® Omega3 Wound, Isafjordur, Iceland).

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