Xpert®MTB/RIF for the Diagnosis of Tuberculosis in a Remote Arctic Setting: Impact on Cost and Time to Treatment Initiation.

Tuberculosis (TB) remains a significant health problem in the Canadian Arctic. Substantial health system delays in TB diagnosis can occur, in part due to the lack of capacity for onsite microbiologic testing. A study recently evaluated the yield and impact of a rapid automated PCR test (Xpert®MTB/RI...

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Bibliographic Details
Published in:PLOS ONE
Main Authors: Oxlade, Olivia, Sugarman, Jordan, Alvarez, Gonzalo G, Pai, Madhukar, Schwartzman, Kevin
Format: Article in Journal/Newspaper
Language:English
Published: Public Library of Science 2016
Subjects:
Iqaluit
Nunavut
Online Access:https://doi.org/10.1371/journal.pone.0150119
https://pubmed.ncbi.nlm.nih.gov/26990299
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4798714/
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Summary:Tuberculosis (TB) remains a significant health problem in the Canadian Arctic. Substantial health system delays in TB diagnosis can occur, in part due to the lack of capacity for onsite microbiologic testing. A study recently evaluated the yield and impact of a rapid automated PCR test (Xpert®MTB/RIF) for the diagnosis of TB in Iqaluit (Nunavut). We conducted an economic analysis to evaluate the expected cost relative to the expected reduction in time to treatment initiation, with the addition of Xpert®MTB/RIF to the current diagnostic and treatment algorithms used in this setting.

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