Morphological and molecular characterization of developing vertebral fusions using a teleost model.
Spinal disorders are a major cause of disability for humans and an important health problem for intensively farmed animals. Experiments have shown that vertebral deformities present a complex but comparable etiology across species. However, the underlying molecular mechanisms involved in bone deform...
| Published in: | BMC Physiology |
|---|---|
| Main Authors: | , , , |
| Format: | Article in Journal/Newspaper |
| Language: | English |
| Published: |
BioMed Central
2010
|
| Subjects: | |
| Online Access: | https://doi.org/10.1186/1472-6793-10-13 https://pubmed.ncbi.nlm.nih.gov/20604916 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2909226/ |
| Summary: | Spinal disorders are a major cause of disability for humans and an important health problem for intensively farmed animals. Experiments have shown that vertebral deformities present a complex but comparable etiology across species. However, the underlying molecular mechanisms involved in bone deformities are still far from understood. To further explicate the mechanisms involved, we have examined the fundamental aspects of bone metabolism and pathogenesis of vertebral fusions in Atlantic salmon (Salmo salar). |
|---|