Organ-related distribution of phospholemman in the spiny dogfish Squalus acanthias

The distribution of phospholemman among nine different organs of the spiny dogfish (Squalus acanthias) has been determined on the basis of Western blotting of microsomal material. Only rectal gland (100%), brain (43%), heart (18%), and kidney (19%) (abundancies as percent of the concentration in rec...

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Bibliographic Details
Published in:Biochemical and Biophysical Research Communications
Main Authors: Schuurmans Stekhoven, F., Grell, E., Atsma, W., Flik, G., Wendelaar Bonga, S.
Format: Article in Journal/Newspaper
Language:English
Published: 2003
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Online Access:http://hdl.handle.net/11858/00-001M-0000-0024-DBCC-C
Description
Summary:The distribution of phospholemman among nine different organs of the spiny dogfish (Squalus acanthias) has been determined on the basis of Western blotting of microsomal material. Only rectal gland (100%), brain (43%), heart (18%), and kidney (19%) (abundancies as percent of the concentration in rectal gland) contained the protein, but not gill and colon. The relative abundance in the brain makes this organ a preferential test system for phospholemman in fishes that lack a rectal gland like teleosts.