Studies in iodine metabolism: Progress report, July 1968-July 1969

• Main Author: Van Middlesworth, L.
• Language: unknown
• Published: 2017
• Subjects: 63 RADIATION; THERMAL; AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; 45 MILITARY TECHNOLOGY; WEAPONRY; AND NATIONAL DEFENSE; 54 ENVIRONMENTAL SCIENCES; IODIDES; METABOLISM; IODINE 131; RADIOECOLOGICAL CONCENTRATION; THIOCYANATES; BLOOD CHEMISTRY; THYROID; BIOLOGICAL RADIATION EFFECTS; THYROXINE; AUTORADIOGRAPHY; CHROMATOGRAPHY; FRACTIONATION; GEL PERMEATION CHROMATOGRAPHY; GLOBAL FALLOUT; PRENATAL EXPOSURE; RATS; SHEEP; AMINO ACIDS; ANIMALS; ANTITHYROID DRUGS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BIOLOGICAL EFFECTS; BODY; CARBONIC ACID DERIVATIVES; CARBOXYLIC ACIDS; DAYS LIVING RADIOISOTOPES; DOMESTIC ANIMALS; DRUGS; ECOLOGICAL CONCENTRATION; ENDOCRINE GLANDS; FALLOUT; GLANDS; HALIDES; HALOGEN COMPOUNDS; HORMONE ANTAGONISTS; HORMONES; INTERMEDIATE MASS NUCLEI; IODINE COMPOUNDS; IODINE ISOTOPES; ISOTOPES; MAMMALS; NUCLEI; Carbonic acid
• Online Access: http://www.osti.gov/servlets/purl/6217942; https://www.osti.gov/biblio/6217942; https://doi.org/10.2172/6217942

This document describes research on iodine metabolism conducted at the University of Tennessee, Memphis between July 1968 and July 1969. The author and his research team prepared autoradiographs of rat thyroids from individuals exposed to Iodine 125 in utero. Additional studies were conducted to determine the effect on hypothalamic lesions on iodide metabolism in rats; to evaluate an iodide-specific electrode for measuring iodide levels in blood or urine; and to study the amount of thyroxine absorption from the intestine. An analysis of bovine and sheep thyroids from eight locations provided additional information on global fallout levels. 21 figs., 2 tabs.