Lipase-catalyzed synthesis of L-cysteine glucosyl esters in organic media

• Published in: Biocatalysis and Biotransformation
• Main Authors: Valepyn, Emmanuel, Nys, Joël, Richel, Aurore, Laurent, Pascal, Berezina, Nathalie, Talon, Olivier, Paquot, Michel
• Format: Article in Journal/Newspaper
• Language: English
• Published: Taylor & Francis Ltd 2011
• Subjects: sugar amino acids; enzymatic synthesis; esterification; lipase; organic media; Life sciences; Biochemistry; biophysics & molecular biology; Sciences du vivant; Biochimie; biophysique & biologie moléculaire; Antarc*; Antarctica
• Online Access: https://orbi.uliege.be/handle/2268/83506; https://doi.org/10.3109/10242422.2010.548555

peer reviewed New sugar amino acids were synthesized by enzymatic esterification of D -glucose with L -cysteine using immobilized lipase B from Candida antarctica in a mixed solvent system composed of 2-methyl-2-butanol and dimethyl sulfoxide. Addition of small quantities of water to the medium improved the glucose conversion yield by a factor of two.